Evidence map›Paper›PMID 29800491›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

Toward Cleavable Metabolic/pH Sensing "Double Agents" Hyperpolarized by NMR Signal Amplification by Reversible Exchange.

Bryce E Kidd, Jamil A Mashni, Miranda N Limbach, Fan Shi, Eduard Y Chekmenev, Yuqing Hou, Boyd M Goodson

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Molecular Fragmentation as a Strategy to Access Hyperpolarized Compounds from Para-Hydrogen.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
    Article
  2. Article
  3. Review
  4. Order-UnityChemphyschem : a European journal of chemical physics and physical chemistry · 2022
    Article
  5. Synthetic Approaches forChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  6. Hyperpolarizing Concentrated MetronidazoleChemistry (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  7. The journal of physical chemistry. C, Nanomaterials and interfaces · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bryce E KiddDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL, 62901, USA.
Jamil A MashniDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL, 62901, USA.
Miranda N LimbachDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL, 62901, USA.
Fan ShiDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL, 62901, USA.
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (Ibio), Wayne State University, Karmanos Cancer Institute (KCI), Detroit, MI, 48202, USA.ORCID http://orcid.org/0000-0002-8745-8801
Yuqing HouDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL, 62901, USA.
Boyd M GoodsonDepartment of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL, 62901, USA.ORCID http://orcid.org/0000-0001-6079-5077

Funding

Pure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB020323 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2015 to 2016
$416k
Magnetic Resonance Spectroscopy and Molecular Imaging of Metabolic Pathways in CancerR21CA220137 · NCI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2017 to 2019
$390k
NCI NIH HHS R21 CA220137NIBIB NIH HHS R21 EB020323
6 · The paper itself

Abstract

We show the simultaneous generation of hyperpolarized

Indexed as

hyperpolarizationmolecular imagingparahydrogenSABRE-SHEATHspin relay

Identifiers

PMID29800491
PMCPMC6097920

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.