Evidence map›Paper›PMID 29800416›Full record

ArticleCardiovascular research2018

Urocortin 2: will a drug targeting both the vasculature and the right ventricle be the future of pulmonary hypertension therapy?

Kurt R Stenmark, Brian B Graham

Open access · bronzeAbstract readEditorialComment
In one paragraph

Article in Cardiovascular research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kurt R StenmarkCardiovascular Pulmonary Research Laboratories, Departments of Pediatrics and Medicine; and.
Brian B GrahamCardiovascular Pulmonary Research Laboratories, Departments of Pediatrics and Medicine; and.
University of Colorado Anschutz Medical Campus · US

Funding

VRAC and Rho in pulmonary EC proliferationP01HL014985 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI STENMARK, KURT R. · 1985 to 2019
$35.1M
Investigating paclitaxel treatment in a pre-clinical model of Schistosoma-pulmonary hypertensionR01HL135872 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Brian Barkley Graham · 2017 to 2026
$5.1M
Role of Th2 CD4 T Cells in Schistosoma Pulmonary HypertensionR03HL133306 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI GRAHAM, BRIAN BARKLEY · 2016 to 2017
$156k
NHLBI NIH HHS P01 HL014985NHLBI NIH HHS R01 HL135872NHLBI NIH HHS R03 HL133306
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryVentricular Function, RightDrug Delivery SystemsHeart VentriclesHumansUrocortinsUrocortins

Identifiers

PMID29800416
PMCPMC6279057
OpenAlexW2804237360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.