Evidence map›Paper›PMID 29800267›Full record

ReviewCardiovascular research2018

Non-coding RNAs in vascular disease - from basic science to clinical applications: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology.

Jan Fiedler, Andrew H Baker, Stefanie Dimmeler, Stephane Heymans, Manuel Mayr, Thomas Thum

Open access · bronzeAbstract readReview
In one paragraph

Review in Cardiovascular research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Noncoding RNA Contribution to Aging and Lifespan.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. MicroRNA-34a: the bad guy in age-related vascular diseases.Cellular and molecular life sciences : CMLS · 2021
    Review
  13. CAD increases the long noncoding RNAMolecular therapy. Nucleic acids · 2021
    Article
  14. Article
  15. Review
  16. Non-coding RNAs in ossification of spinal ligament.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Review
  17. Article
  18. Review
  19. Article
  20. Vascular smooth muscle cells in atherosclerosis.Nature reviews. Cardiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Jan FiedlerInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Str.1, 30625 Hannover, Germany.
Andrew H BakerCentre for Cardiovascular Sciences, Queen's Medical Research Institute, Edinburgh, UK.
Stefanie DimmelerInstitute for Cardiovascular Regeneration, Goethe University, Frankfurt am Main, Germany.
Stephane HeymansCardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Manuel MayrKing's British Heart Foundation Centre, King's College London, London, UK.
Thomas ThumInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Str.1, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DEGoethe University Frankfurt · DEKing's College London · GBMaastricht University Medical Centre · NLThe Queen's Medical Research Institute · GB

Funding

British Heart Foundation CH/16/3/32406British Heart Foundation RG/16/14/32397British Heart Foundation SP/17/10/33219Department of Health
6 · The paper itself

Abstract

Non-coding RNAs are increasingly recognized not only as regulators of various biological functions but also as targets for a new generation of RNA therapeutics and biomarkers. We hereby review recent insights relating to non-coding RNAs including microRNAs (e.g. miR-126, miR-146a), long non-coding RNAs (e.g. MIR503HG, GATA6-AS, SMILR), and circular RNAs (e.g. cZNF292) and their role in vascular diseases. This includes identification and therapeutic use of hypoxia-regulated non-coding RNAs and endogenous non-coding RNAs that regulate intrinsic smooth muscle cell signalling, age-related non-coding RNAs, and non-coding RNAs involved in the regulation of mitochondrial biology and metabolic control. Finally, we discuss non-coding RNA species with biomarker potential.This article is part of the Mini Review Series from the Varenna 2017 meeting of the Working Group of Myocardial Function of the European Society of Cardiology.

Indexed as

Blood VesselsAge FactorsAnimalsCell HypoxiaCellular MicroenvironmentCirculating MicroRNAEnergy MetabolismGene Expression RegulationGenetic MarkersHumansPrognosisRisk FactorsRNARNA, CircularRNA, Long NoncodingRNA, UntranslatedCirculating MicroRNAGenetic MarkersRNARNA, CircularRNA, Long NoncodingRNA, Untranslated

Identifiers

PMID29800267
PMCPMC6054241
OpenAlexW2803165459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.