Evidence map›Paper›PMID 29800013›Full record

ReviewJAMA neurology2018

Cluster Headache Is in Part a Disorder of the Circadian System.

Mark J Burish, Zheng Chen, Seung-Hee Yoo

Abstract readReview
In one paragraph

Review in JAMA neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
  4. Smoking and cluster headache: clinical, gender, and treatment insights from a cross-sectional cluster analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  5. Hallmarks of primary headache: part 3 - cluster headache.The journal of headache and pain · 2025
    Review
  6. BioClocks UK: driving robust cycles of discovery to impact.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. The molecular clock gene cryptochrome 1 (Cephalalgia : an international journal of headache · 2021
    Article
  16. Circadian rhythm as a therapeutic target.Nature reviews. Drug discovery · 2021
    Review
  17. Seizure Cycles in Focal Epilepsy.JAMA neurology · 2021
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark J BurishDepartment of Neurosurgery, University of Texas Health Science Center at Houston.
Zheng ChenDepartment of Biochemistry and Molecular Biology, University of Texas Health Science Center at Houston.
Seung-Hee YooDepartment of Biochemistry and Molecular Biology, University of Texas Health Science Center at Houston.

Funding

Regulation and function of the circadian factor Period2R01GM114424 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YOO, SEUNG-HEE · 2015 to 2019
$1.6M
Role of Clock-Modulating Small Molecules Against AgingR01AG045828 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHEN, ZHENG · 2013 to 2017
$1.4M
NIA NIH HHS R01 AG045828NIGMS NIH HHS R01 GM114424
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BrainChronobiology DisordersCircadian RhythmCluster HeadacheHumansMelatoninNerve NetMelatonin

Identifiers

PMID29800013
PMCPMC6390835

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.