Evidence map›Paper›PMID 29799766›Full record

ReviewAnnual review of nutrition2018

Nutritional Influences on One-Carbon Metabolism: Effects on Arsenic Methylation and Toxicity.

Anne K Bozack, Roheeni Saxena, Mary V Gamble

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 7 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 7 syntheses or guidelines pooled it, 98 citations in OpenAlex.

  1. Pooled it
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  11. Article
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  15. Article
  16. Review
  17. Arsenome, Arsenobolome, and Arsenobiolome.International journal of molecular sciences · 2025
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anne K BozackDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; email: mvg7@cumc.columbia.edu.
Roheeni SaxenaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; email: mvg7@cumc.columbia.edu.
Mary V GambleDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; email: mvg7@cumc.columbia.edu.
Columbia University · US

Funding

Training CoreP42ES010349 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA · 2000 to 2020
$53.6M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Folic Acid and Creatine as Therapeutic Approaches for Lowering Blood ArenicR01CA133595 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2009 to 2013
$2.3M
Biomarkers for Arsenic Toxicity: Genetics, Epigenetics and FolateR01ES017875 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GAMBLE, MARY · 2010 to 2013
$1.9M
Effects of Arsenic Exposure on 5-methylcytosine and 5-hydroxymethylcytosine, and Effect Modification by Nutritional StatusF31ES029019 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BOZACK, ANNE KRISTINA · 2018 to 2019
$48k
NCI NIH HHS R01 CA133595NIEHS NIH HHS F31 ES029019NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P42 ES010349NIEHS NIH HHS R01 ES017875NIEHS NIH HHS T32 ES007322
6 · The paper itself

Abstract

Exposure to inorganic arsenic (InAs) via drinking water and/or food is a considerable worldwide problem. Methylation of InAs generates monomethyl (MMAs

Indexed as

Nutritional Physiological PhenomenaAnimalsArsenicCarbonDietary ExposureHumansMethylationArsenicCarbonarsenicarsenic methylationfolatenutritionone-carbon metabolism

Identifiers

PMID29799766
PMCPMC6441546
OpenAlexW2803267096

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.