ArticleArthritis care & research2019
Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout.
Article in Arthritis care & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04012294 (Effects of Allopurinol on Inflammatory Markers and Morphostructural Changes Evidenced by Musculoskeletal Ultrasound in Individuals With Asymptomatic Hyperuricemia. A Proof of Concept), which is not on this map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Allopurinol on Inflammatory Markers and Morphostructural Changes Evidenced by Musculoskeletal Ultrasound in Individuals With Asymptomatic Hyperuricemia. A Proof of Concept
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Multidimensional therapeutic advantages ofFrontiers in endocrinology · 2026Pooled it
- Dietary supplements for chronic gout.The Cochrane database of systematic reviews · 2021Pooled it
- Lack of evidence for allopurinol for the prevention of a first gout attack in asymptomatic hyperuricemia: a systematic review.European journal of clinical pharmacology · 2020Pooled it
- Endothelial injury and inflammation in patients with hyperuricemic nephropathy at chronic kidney disease stages 1-2 and 3-4.World journal of clinical cases · 2022Trial
- Importance of Considering the Gout Flare: Let's Learn to Walk and Chew Gum at the Same Time in Gout Clinical Trial Design.Arthritis & rheumatology (Hoboken, N.J.) · 2025Article
- Physical Impairments in People With Gout: A Scoping Review.Musculoskeletal care · 2025Article
- Article
- Prediction of Monosodium Urate Crystal Deposits in the First Metatarsophalangeal Joint Using a Decision Tree ModelCurrent medical imaging · 2025Article
- Protective effects of polysaccharide SH-P-1-1 isolated fromFrontiers in nutrition · 2025Article
- The Status Quo and Influencing Factors of Self-Management Behavior in Patients with Recurrent Gout in China: A Cross-Sectional Study.Patient preference and adherence · 2025Article
- Exercise and hyperuricemia: an opinion article.Annals of medicine · 2024Article
- Understanding the interplay between psoriatic arthritis and gout: "Psout".Rheumatology international · 2024Review
- Role of Chemotaxis of Vδ2 T Cells to the Synovium in the Pathogenesis of Acute Gouty Arthritis.Journal of inflammation research · 2024Article
- The impact of AIM2 inflammasome-induced pyroptosis on acute gouty arthritis and asymptomatic hyperuricemia patients.Frontiers in immunology · 2024Article
- Identification of inhibitors from a functional food-based plant Perillae Folium against hyperuricemia via metabolomics profiling, network pharmacology and all-atom molecular dynamics simulations.Frontiers in endocrinology · 2024Article
- Development and validation of a prediction nomogram for depressive symptoms in gout patients.Frontiers in public health · 2024Article
- Hyperuricemia is accompanied by elevated peripheral CD4Scientific reports · 2023Article
- Rapidly separating dissolving microneedles with sustained-release colchicine and stabilized uricase for simplified long-term gout management.Acta pharmaceutica Sinica. B · 2023Article
- What are the core recommendations for gout management in first line and specialist care? Systematic review of clinical practice guidelines.BMC rheumatology · 2023Article
- Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.Antioxidants (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
56 authors at 20 institutions in 19 countries.
Funding
Abstract
objectiveThe language currently used to describe gout lacks standardization. The aim of this project was to develop a consensus statement on the labels and definitions used to describe the basic disease elements of gout.
methodsExperts in gout (n = 130) were invited to participate in a Delphi exercise and face-to-face consensus meeting to reach consensus on the labeling and definitions for the basic disease elements of gout. Disease elements and labels in current use were derived from a content analysis of the contemporary medical literature, and the results of this analysis were used for item selection in the Delphi exercise and face-to-face consensus meeting.
resultsThere were 51 respondents to the Delphi exercise and 30 attendees at the face-to-face meeting. Consensus agreement (≥80%) was achieved for the labels of 8 disease elements through the Delphi exercise; the remaining 3 labels reached consensus agreement through the face-to-face consensus meeting. The agreed labels were monosodium urate crystals, urate, hyperuric(a)emia, tophus, subcutaneous tophus, gout flare, intercritical gout, chronic gouty arthritis, imaging evidence of monosodium urate crystal deposition, gouty bone erosion, and podagra. Participants at the face-to-face meeting achieved consensus agreement for the definitions of all 11 elements and a recommendation that the label "chronic gout" should not be used.
conclusionConsensus agreement was achieved for the labels and definitions of 11 elements representing the fundamental components of gout etiology, pathophysiology, and clinical presentation. The Gout, Hyperuricemia, and Crystal-Associated Disease Network recommends the use of these labels when describing the basic disease elements of gout.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.