ArticleMedical physics2018
A Novel method to generate on-board 4D MRI using prior 4D MRI and on-board kV projections from a conventional LINAC for target localization in liver SBRT.
Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Real-time 3D synthetic MRI based on kV imaging for motion monitoring of abdominal radiotherapy in a conventional LINAC.Physics in medicine and biology · 2025Article
- On-board synthetic 4D MRI generation from 4D CBCT for radiotherapy of abdominal tumors: A feasibility study.Medical physics · 2024Article
- A review on 4D cone-beam CT (4D-CBCT) in radiation therapy: Technical advances and clinical applications.Medical physics · 2024Review
- A dual-supervised deformation estimation model (DDEM) for constructing ultra-quality 4D-MRI based on a commercial low-quality 4D-MRI for liver cancer radiation therapy.Medical physics · 2022Article
- Evaluation of Multisource Adaptive MRI Fusion for Gross Tumor Volume Delineation of Hepatocellular Carcinoma.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
Abstract
purposeOn-board MRI can provide superb soft tissue contrast for improving liver SBRT localization. However, the availability of on-board MRI in clinics is extremely limited. On the contrary, on-board kV imaging systems are widely available on radiotherapy machines, but its capability to localize tumors in soft tissue is limited due to its poor soft tissue contrast. This study aims to explore the feasibility of using an on-board kV imaging system and patient prior knowledge to generate on-board four-dimensional (4D)-MRI for target localization in liver SBRT.
methodsPrior 4D MRI volumes were separated into end of expiration (EOE) phase (MRI
resultsIn the XCAT study, VPD/VDC/COMS among all XCAT scenarios were 10.16 ± 1.31%/0.95 ± 0.01/0.88 ± 0.15 mm using orthogonal-view 30° scan angles with 102 projections. The on-board 4D MRI method was robust against the various scan angles and projection numbers evaluated. In the patient study, estimated on-board 4D MRI was generated successfully when compared to the "reference on-board 4D MRI" for the liver patient case.
conclusionsA method was developed to generate on-board 4D MRI using prior 4D MRI and on-board limited kV projections. Preliminary results demonstrated the potential for MRI-based image guidance for liver SBRT using only a kV imaging system on a conventional LINAC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.