ArticleJournal of neural engineering2018
Wireless opto-electro neural interface for experiments with small freely behaving animals.
Article in Journal of neural engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- A wireless optogenetic stimulation system for long-term function evaluation of mice forelimb with sub-nerve resolution.Nature communications · 2025Article
- An Energy-Efficient and Artifact-Resilient ASIC for Simultaneous Neural Recording and Optogenetic Stimulation.IEEE transactions on biomedical circuits and systems · 2025Article
- Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems.Bioactive materials · 2025Review
- Low-Power Lossless Data Compression for Wireless Brain Electrophysiology.Sensors (Basel, Switzerland) · 2022Article
- Flexible optoelectric neural interfaces.Current opinion in biotechnology · 2021Review
- How is flexible electronics advancing neuroscience research?Biomaterials · 2021Review
- A Trimodal Wireless Implantable Neural Interface System-on-Chip.IEEE transactions on biomedical circuits and systems · 2020Article
- Enlightening the frontiers of neurogastroenterology through optogenetics.American journal of physiology. Gastrointestinal and liver physiology · 2020Review
- A mm-Sized Free-Floating Wireless Implantable Opto-Electro Stimulation Device.Micromachines · 2020Article
- A Software-Defined Radio Receiver for Wireless Recording From Freely Behaving Animals.IEEE transactions on biomedical circuits and systems · 2019Article
- A Dual-Band Wireless Power Transmission System for Evaluating mm-Sized Implants.IEEE transactions on biomedical circuits and systems · 2019Article
- A mm-Sized Free-Floating Wirelessly Powered Implantable Optical Stimulation Device.IEEE transactions on biomedical circuits and systems · 2019Article
- An Inductively-Powered Wireless Neural Recording and Stimulation System for Freely-Behaving Animals.IEEE transactions on biomedical circuits and systems · 2019Article
- Telemetry-controlled simultaneous stimulation-and-recording device (SRD) to study interhemispheric cortical circuits in rat primary somatosensory (SI) cortex.BMC biomedical engineering · 2019Article
- Inductively coupled, mm-sized, single channel optical neuro-stimulator with intensity enhancer.Microsystems & nanoengineering · 2019Article
- Implantable Neural Probes for Brain-Machine Interfaces - Current Developments and Future Prospects.Experimental neurobiology · 2018Review
- Wireless opto-electro neural interface for experiments with small freely behaving animals.Journal of neural engineering · 2018Article
- A High-Resolution Opto-Electrophysiology System With a Miniature Integrated Headstage.IEEE transactions on biomedical circuits and systems · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveWe have developed a wireless opto-electro interface (WOENI) device, which combines electrocorticogram (ECoG) recording and optical stimulation for bi-directional neuromodulation on small, freely behaving animals, such as rodents. APPROACH: The device is comprised of two components, a detachable headstage and an implantable polyimide-based substrate. The headstage establishes a bluetooth low energy (BLE) bi-directional data communication with an external custom-designed USB dongle for receiving user commands and optogenetic stimulation patterns, and sending digitalized ECoG data. MAIN
resultsThe functionality and stability of the device were evaluated in vivo on freely behaving rats. When the animal received optical stimulation on the primary visual cortex (V1) and visual stimulation via eyes, spontaneous changes in ECoG signals were recorded from both left and right V1 during four consecutive experiments with 7 d intervals over a time span of 21 d following device implantation. Immunostained tissue analyses showed results consistent with ECoG analyses, validating the efficacy of optical stimulation to upregulate the activity of cortical neurons expressing ChR2. SIGNIFICANCE: The proposed WOENI device is potentially a versatile tool in the studies that involve long-term optogenetic neuromodulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.