ArticleNeurocase2018
Clinical and imaging progression over 10 years in a patient with primary progressive apraxia of speech and autopsy-confirmed corticobasal degeneration.
Article in Neurocase, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech.Nature communications · 2021Trial
- Progression to corticobasal syndrome: a longitudinal study of patients with nonfluent primary progressive aphasia and primary progressive apraxia of speech.Journal of neurology · 2024Article
- Combined assessment of progressive apraxia of speech brain microstructure by diffusion tensor imaging tractography and multishell neurite orientation dispersion and density imaging.Brain and behavior · 2024Article
- An Update on Apraxia of Speech.Current neurology and neuroscience reports · 2023Review
- Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech.European journal of neurology · 2023Article
- A Patient with Corticobasal Syndrome and Progressive Non-Fluent Aphasia (CBS-PNFA), with Variants inGenes · 2022Article
- Functional connectivity to the premotor cortex maps onto longitudinal brain neurodegeneration in progressive apraxia of speech.Neurobiology of aging · 2022Article
- Neuropsychological Profiles of Patients with Progressive Apraxia of Speech and Aphasia.Journal of the International Neuropsychological Society : JINS · 2022Article
- Autopsy Validation of Progressive Supranuclear Palsy-Predominant Speech/Language Disorder Criteria.Movement disorders : official journal of the Movement Disorder Society · 2022Article
- Progressive apraxia of speech: delays to diagnosis and rates of alternative diagnoses.Journal of neurology · 2021Article
- Survival Analysis in Primary Progressive Apraxia of Speech and Agrammatic Aphasia.Neurology. Clinical practice · 2021Article
- Article
- The evolution of parkinsonism in primary progressive apraxia of speech: A 6-year longitudinal study.Parkinsonism & related disorders · 2020Article
- Ioflupane 123I (DAT scan) SPECT identifies dopamine receptor dysfunction early in the disease course in progressive apraxia of speech.Journal of neurology · 2020Article
- Longitudinal flortaucipir ([Cortex; a journal devoted to the study of the nervous system and behavior · 2020Article
- Nuclear Imaging in the Diagnosis of Clinically Uncertain Parkinsonian Syndromes.Deutsches Arzteblatt international · 2019Review
- An Evaluation of the Progressive Supranuclear Palsy Speech/Language Variant.Movement disorders clinical practice · 2019Article
- FTD spectrum: Neuroimaging across the FTD spectrum.Progress in molecular biology and translational science · 2019Review
- Coming to Terms with a Conundrum: A Case of Primary Progressive Apraxia of Speech due to Corticobasal Degeneration?Case reports in neurologyArticle
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Authors and funding
11 authors.
Funding
Abstract
Primary progressive apraxia of speech (PPAOS) is a neurodegenerative disorder in which AOS is the sole presenting complaint. We report clinical and neuroimaging data spanning 10 years from disease onset-to-death in a 49 year-old male PPAOS patient, DY, who died with corticobasal degeneration. He presented with AOS with normal neuroimaging. Abnormalities in the caudate nucleus, supplementary motor area, cingulate, insula, and Broca's area were observed after five years, with involvement of motor cortex and development of agrammatism, Parkinsonism, and dysarthria three years later. Cognitive impairment and temporoparietal atrophy were late features. This data provides important insight into disease progression of corticobasal degeneration when presenting as PPAOS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.