Evidence map›Paper›PMID 29799157›Full record

ArticleJournal of cellular and molecular medicine2018

Aldehyde dehydrogenase 2 activation ameliorates CCl

Xin Ma, Qin Luo, Hong Zhu, Xuejing Liu, Zhen Dong, Kaili Zhang, Yunzeng Zou, Jian Wu, Junbo Ge, Aijun Sun

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
  2. ALDH2 Mediated Ferroptosis Regulation in Ischemia-Reperfusion Injury.Journal of cellular and molecular medicine · 2026
    Review
  3. Article
  4. Article
  5. Resveratrol ameliorates CClMolecular biology reports · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Hesperidin ameliorates HJournal of animal science and biotechnology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xin MaInstitute of Biomedical Sciences, Fudan University, Shanghai, China.
Qin LuoInstitute of Biomedical Sciences, Fudan University, Shanghai, China.
Hong ZhuDepartment of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Xuejing LiuDepartment of Medical Microbiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Zhen DongDepartment of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Kaili ZhangInstitute of Biomedical Sciences, Fudan University, Shanghai, China.
Yunzeng ZouInstitute of Biomedical Sciences, Fudan University, Shanghai, China.
Jian WuDepartment of Medical Microbiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Junbo GeInstitute of Biomedical Sciences, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-8318-4882
Aijun SunInstitute of Biomedical Sciences, Fudan University, Shanghai, China.
Sun Yat-sen University · CNFudan University · CNShanghai Medical College of Fudan University · CN

Funding

Innovative Research Groups of the National Natural Science Foundation of China 81521001National Natural Science Foundation of China 81272436National Natural Science Foundation of China 81570224National Natural Science Foundation of China 81572356Shanghai Commission of Sciences and Technologies 16140903700The Ministry of Science & Technology of China 2016YFE0107400
6 · The paper itself

Abstract

Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is critical in the pathogenesis of alcoholic liver cirrhosis. However, the effect of ALHD2 on liver fibrosis remains to be further elucidated. This study aimed to demonstrate whether ALDH2 regulates carbon tetrachloride (CCl

Indexed as

Alda-1ALDH2CCl4liver fibrosismitophagyNrf2/HO-1

Identifiers

PMID29799157
PMCPMC6050510
OpenAlexW2804020656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.