Evidence map›Paper›PMID 29799066›Full record

ReviewWorld journal of microbiology & biotechnology2018

Genome characteristics dictate poly-R-(3)-hydroxyalkanoate production in Cupriavidus necator H16.

Gurusamy Kutralam-Muniasamy, Fermín Peréz-Guevara

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gurusamy Kutralam-MuniasamyDepartment of Biotechnology and Bioengineering, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Av. IPN 2508, Zacatenco Gustavo A. Madero, México D.F., Mexico.
Fermín Peréz-GuevaraDepartment of Biotechnology and Bioengineering, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Av. IPN 2508, Zacatenco Gustavo A. Madero, México D.F., Mexico. fermin@cinvestav.mx.
Center for Research and Advanced Studies of the National Polytechnic Institute · MX

Funding

CONACyT CB-2014-01; 236285 and Fronteras de la Ciencia 2015-1: 016
6 · The paper itself

Abstract

Cupriavidus necator H16 is a well-recognized enterprise with efficient manufacturing machineries to produce diverse polymers belonging to polyhydroxyalkanoates (PHAs) family. The genome fingerprints, including PHA machinery proteins and fatty acid metabolism, had educated engineering strategies to enhance PHAs production. This outstanding progress has enlightened us to present an exhaustive examination of the ongoing research, addressing the great potential design of genome features towards PHA production and furthermore, we show how those acquired knowledge have been explored in other biotechnological applications. This updated-review concludes that the combination of an optimal strain selection, suitable metabolic engineering and a large-scale fermentation on oil substrates is critical to endow the ability of incorporating mcl-PHAs monomers in this organism.

Indexed as

Bacterial ProteinsBiofuelsBiotechnologyCupriavidus necatorFermentationGene Expression ProfilingGene Expression Regulation, BacterialMetabolic EngineeringMetabolic Networks and PathwaysMultigene FamilyMutationPolyhydroxyalkanoatesBacterial ProteinsBiofuelsPolyhydroxyalkanoatesBiofuelsMedium chain lengthMetabolic engineeringMutantsPhasinsPHA synthase

Identifiers

PMID29799066
OpenAlexW2804539202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.