Evidence map›Paper›PMID 29797664›Full record

ArticleCancer2018

Association between patient-reported hearing and visual impairments and functional, psychological, and cognitive status among older adults with cancer.

Enrique Soto-Perez-de-Celis, Can-Lan Sun, William P Tew, Supriya Gupta Mohile, Ajeet Gajra, Heidi D Klepin, Cynthia Owusu, Cary Philip Gross, Hyman B Muss, Stuart M Lichtman and 7 more

Abstract read
In one paragraph

Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Recommendations from the Geriatric Oncology Working Group of the Spanish Society of Radiation Oncology for the treatment of elderly patients with radiotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  13. Unrealistic expectations and disclosure of incurability in patients with non-small cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  14. Review
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  18. Article
  19. Understanding Treatment Tolerability in Older Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Enrique Soto-Perez-de-CelisCancer and Aging Research Program, City of Hope, Duarte, California.ORCID 0000-0002-7301-2163
Can-Lan SunCancer and Aging Research Program, City of Hope, Duarte, California.
William P TewDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Supriya Gupta MohileDepartment of Medicine, University of Rochester Medical Center, Rochester, New York.
Ajeet GajraICON Clinical Research, North Wales, Pennsylvania.
Heidi D KlepinDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Cynthia OwusuDepartment of Medicine, Case Western Reserve University, Cleveland, Ohio.ORCID 0000-0003-2045-4336
Cary Philip GrossDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Hyman B MussUniversity of North Carolina School of Medicine, Chapel Hill, North Carolina.
Stuart M LichtmanDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Andrew E ChapmanJefferson Senior Adult Oncology Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
Harvey Jay CohenCenter for the Study of Aging & Human Development, Duke University Medical Center, Durham, North Carolina.
William DaleDepartment of Supportive Care Medicine, City of Hope, Duarte, California.
Heeyoung KimCancer and Aging Research Program, City of Hope, Duarte, California.
Simone FernandesCancer and Aging Research Program, City of Hope, Duarte, California.
Vani KatheriaCancer and Aging Research Program, City of Hope, Duarte, California.
Arti HurriaCancer and Aging Research Program, City of Hope, Duarte, California.ORCID 0000-0001-7983-9615

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
A Patient-Oriented Research Program in Geriatric OncologyK24AG056589 · NIA · UNIVERSITY OF ROCHESTER · PI Supriya G. Mohile · 2018 to 2026
$1.5M
Mentoring the Next Generation of Geriatric Oncology Researchers in Patient-Oriented Research to Improve the Care of Older Adults with CancerK24AG055693 · NIA · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI WILLIAM DALE · 2018 to 2026
$1.4M
Can Geriatric Assessment Predict Oncology Outcomes?K23AG026749 · NIA · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI HURRIA, ARTI · 2005 to 2009
$874k
NCI NIH HHS P30 CA008748NCI NIH HHS UG1 CA189961NIA NIH HHS K23 AG026749NIA NIH HHS K24 AG055693NIA NIH HHS K24 AG056589
6 · The paper itself

Abstract

backgroundHearing and visual impairments are common among community-dwelling older adults, and are associated with psychological, functional, and cognitive deficits. However, to the authors' knowledge, little is known regarding their prevalence among older patients with cancer.

methodsThe current study was a secondary analysis combining 2 prospective cohorts of adults aged ≥65 years with solid tumors who were receiving chemotherapy. The authors assessed the association between patient-reported hearing and/or visual impairment (defined as fair/poor grading by self-report) and physical function, instrumental activities of daily living (IADLs), anxiety, depression, and cognition. Descriptive analyses were conducted to summarize patient and treatment characteristics. One-way analysis of variance and chi-square tests were conducted as appropriate to examine differences between patients with and without sensory impairments. Logistic regression was used to analyze associations between sensory impairments and outcomes.

resultsAmong 750 patients with a median age of 72 years who had solid tumors (29% with breast/gynecological tumors, 28% with lung tumors, and 27% with gastrointestinal tumors), approximately 18% reported hearing impairment alone, 11% reported visual impairment alone, and 7% reported dual sensory impairment. Hearing impairment was associated with IADL dependence (odds ratio [OR], 1.9), depression (OR, 1.6), and anxiety (OR, 1.6). Visual impairment was associated with IADL dependence (OR, 1.9), poor physical function (OR, 1.9), and depression (OR, 2.5). Dual impairment was associated with IADL dependence (OR, 2.8), anxiety (OR, 2.3), depression (OR, 2.5), and cognitive impairment (OR, 3.2).

conclusionsSensory impairment is common among older adults with cancer. Patients with sensory impairment are more likely to have functional, psychological, and cognitive deficits. Interventions aimed at improving the vision and hearing of older adults with cancer should be studied. Cancer 2018. © 2018 American Cancer Society.

Indexed as

Activities of Daily LivingAgedAged, 80 and overCognitionCognitive DysfunctionCross-Sectional StudiesDepressionFemaleGeriatric AssessmentHearing LossHumansMaleNeoplasmsPatient Reported Outcome MeasuresSelf ReportVision Disordersactivities of daily livinganxietycognitive dysfunctiondepressiongeriatric oncologyhearing lossneoplasmsolder adultsvision disorders

Identifiers

PMID29797664
PMCPMC6613937

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.