Observational studyObesity (Silver Spring, Md.)2018
Energy Expenditure in Pregnant Women with Obesity Does Not Support Energy Intake Recommendations.
Observational study in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for inadequate and excessive gestational weight gain in 25 low- and middle-income countries: An individual-level participant meta-analysis.PLoS medicine · 2023Pooled it
- Resting Metabolic Rate Rises in Pregnancy, but Energy Intake and Active Expenditure Remain Stable: A Pilot Study.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- The impact of maternal metabolic flexibility during gestation on infant adiposity in individuals with obesity.American journal of physiology. Endocrinology and metabolism · 2026Article
- Nutrition, Physical Activity and Other Health Aspects Before and During Pregnancy - Recommendations by the Nationwide "Healthy Start Network" (Netzwerk Gesund ins Leben) 2026.Geburtshilfe und Frauenheilkunde · 2026Article
- Weight management in women of reproductive age.Obesity and endocrinology · 2026Review
- Estimating energy requirements from Dietary Reference Intakes for pregnant people with obesity using wearables.Obesity (Silver Spring, Md.) · 2025Article
- Article
- Article
- Comparative Assessment of Diet Quality and Adherence to a Structured Nutrition and Exercise Intervention Compared with Usual Care in Pregnancy in a Randomized Trial.Current developments in nutrition · 2023Article
- Maternal mindful eating as a target for improving metabolic outcomes in pregnant women with obesity.Frontiers in bioscience (Landmark edition) · 2021Observational
- A role for the early pregnancy maternal milieu in the intergenerational transmission of obesity.Obesity (Silver Spring, Md.) · 2021Article
- Eating Behaviors and Dietary Patterns of Women during Pregnancy: Optimizing the Universal 'Teachable Moment'.Nutrients · 2021Article
- Low Resting Energy Expenditure Is Associated with High Gestational Weight Gain Only When Resting Energy Expenditure Fluctuates.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Article
- Identification of changes in sleep across pregnancy and the impact on cardiometabolic health and energy intake in women with obesity.Sleep medicine · 2021Observational
- Increased Energy Intake After Pregnancy Determines Postpartum Weight Retention in Women With Obesity.The Journal of clinical endocrinology and metabolism · 2020Observational
- Body Composition During Pregnancy Differs by Obesity Class.Obesity (Silver Spring, Md.) · 2020Article
- Time to change weight gain recommendations for pregnant women with obesity.The Journal of clinical investigation · 2019Article
- Application of mathematical models in the management of obesity during pregnancy and the postpartum period in reproductive age women.Nutrition research (New York, N.Y.) · 2019Article
- Energy Intake Requirements in Pregnancy.Nutrients · 2019Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveThis study aimed to identify factors that may predispose women to excess gestational weight gain (GWG).
methodsSeventy-two healthy women with obesity (30 class I, 24 class II, 18 class III) expecting a singleton pregnancy were studied at 13 to 16 weeks gestation. Energy expenditure (EE) was measured during sleep (SleepEE, average EE from 0200-0500 hours) in a whole-room calorimeter, and total daily EE (TDEE) over 7 days using doubly labeled water. Glucose, insulin, thyroid hormones, and catecholamines were measured.
resultsBody composition explained 70% variability in SleepEE, and SleepEE accounted for 67% to 73% of TDEE. Though there was no evidence of consistent low metabolism, there was considerable variability. Low SleepEE was associated with insulin resistance and low triiodothyronine concentrations (both P = 0.01). Physical activity level was 1.47 ± 0.02. For women with SleepEE within 100 kcal/d of their predicted EE, TDEE was significantly less than the estimate (2,530 ± 91 vs. 2,939 kcal/d; P < 0.001) provided from the most recent gestational energy requirement model.
conclusionsPregnant women with obesity are inactive, possibly predisposing them to excess GWG. Current energy requirement models overestimate activity and may promote excess GWG in women with obesity. Furthermore, the observed large interindividual variability in basal metabolism may be important to consider when assessing the risk for excess GWG.
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