ArticleAdvanced materials (Deerfield Beach, Fla.)2018
A Rapid and Robust Diagnostic for Liver Fibrosis Using a Multichannel Polymer Sensor Array.
Article in Advanced materials (Deerfield Beach, Fla.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- A Sensitive Multichannel Fluorescent Polymer Sensor Array for the Detection of Protein Fluctuations in Serum.Sensors (Basel, Switzerland) · 2026Article
- Fingerprint profiling human gut microbiota through boronic acid-based sensor array and its application on colorectal cancer classification.Nature communications · 2026Article
- Anthracene-Modified Nanoporous Silica Nanoparticles for ATP Detection and Salivary Diagnostics in Parkinson's Disease.ACS applied nano materials · 2026Article
- Expanding the recognition of monosaccharides and glycans: A comprehensive analytical approach using chemical-nose/tongue technology and a comparison to lectin microarrays.BBA advances · 2025Article
- Fast and accurate identification of pathogenic bacteria using excitation-emission spectroscopy and machine learning.Sensors & diagnostics · 2024Article
- Imaging-guided companion diagnostics in radiotherapy by monitoring APE1 activity with afterglow and MRI imaging.Nature communications · 2024Article
- Colorimetric sensor array for versatile detection and discrimination of model analytes with environmental relevance.BMC chemistry · 2024Article
- Chemical tongues as multipurpose bioanalytical tools for the characterization of complex biological samples.Biophysics and physicobiology · 2024Review
- A cross-reactive plasmonic sensing array for drinking water assessment.Environmental science. Nano · 2023Article
- Sensing of Antibiotic-Bacteria Interactions.Antibiotics (Basel, Switzerland) · 2023Review
- Carbocyanine-Based Optical Sensor Array for the Discrimination of Proteins and Rennet Samples Using Hypochlorite Oxidation.Sensors (Basel, Switzerland) · 2023Article
- Engineered Polymer-siRNA Polyplexes Provide Effective Treatment of Lung Inflammation.ACS nano · 2023Article
- Accurate identification of kidney injury progression via a fluorescent biosensor array.Mikrochimica acta · 2022Article
- Ongoing Clinical Trials in Aging-Related Tissue Fibrosis and New Findings Related to AhR Pathways.Aging and disease · 2022Review
- Direct Cytosolic Delivery of Proteins Using Lyophilized and Reconstituted Polymer-Protein Assemblies.Pharmaceutical research · 2022Article
- Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.Chemical reviews · 2022Review
- Optical Sensor Array for the Early Diagnosis of Alzheimer's Disease.Frontiers in chemistry · 2022Review
- Article
- A Multichannel Pattern-Recognition-Based Protein Sensor with a Fluorophore-Conjugated Single-Stranded DNA Set.Sensors (Basel, Switzerland) · 2020Article
- Clinically accurate diagnosis of Alzheimer's disease via multiplexed sensing of core biomarkers in human plasma.Nature communications · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Liver disease is the fifth most common cause of premature death in the Western world, with the irreversible damage caused by fibrosis, and ultimately cirrhosis, a primary driver of mortality. Early detection of fibrosis would facilitate treatment of the underlying liver disease to limit progression. Unfortunately, most cases of liver disease are diagnosed late, with current strategies reliant on invasive biopsy or fragile lab-based antibody technologies. A robust, fully synthetic fluorescent-polymer sensor array is reported, which, rapidly (in 45 minutes), detects liver fibrosis from low-volume serum samples with clinically relevant specificity and accuracy, using an easily readable diagnostic output. The simplicity, rapidity, and robustness of this method make it a promising platform for point-of-care diagnostics for detecting and monitoring liver disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.