Evidence map›Paper›PMID 29797071›Full record

ArticleWiener klinische Wochenschrift2018

Phenotypes of COPD in an Austrian population : National data from the POPE study.

Gabriele Reiger, Ralf Zwick, Bernd Lamprecht, Christian Kähler, Otto Chris Burghuber, Arschang Valipour

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Article in Wiener klinische Wochenschrift, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  6. Article
  7. Characteristics of COPD Phenotypes in Serbia.International journal of chronic obstructive pulmonary disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Gabriele ReigerSKA-Rehabilitationszentrum der PVA, Weyer, Austria.
Ralf ZwickTherme Wien Med, Ambulante Pneumologische Rehabilitation, Vienna, Austria.
Bernd LamprechtDepartment of Pulmonary Medicine, Kepler University Clinic, Linz, Austria.
Christian KählerKlinik für Pneumologie, Fachkliniken Wangen, Wangen, Germany.
Otto Chris BurghuberMedical School, Sigmund Freud University, Vienna, Austria.
Arschang ValipourDepartment of Respiratory and Critical Care Medicine, Ludwig-Boltzmann-Institute for COPD and Respiratory Epidemiology, Otto-Wagner-Spital, Sanatoriumstraße 2, 1140, Vienna, Austria. arschang.valipour@wienkav.at.
Kepler Universitätsklinikum · ATLandwirtschaftlichen Zentrums Baden-Württemberg​ · DELudwig Boltzmann Institute for COPD And Respiratory Epidemiology · ATSigmund Freud University Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) represents a major global health problem; however, there are no data regarding clinical phenotypes of these patients in Austria.

methodsThis was an analysis from the Austrian cohort of the cross-sectional Phenotypes of COPD in Central and Eastern Europe (POPE) study, which was offered to patients with stable COPD in a real-life setting. Patients were recruited at 5 different outpatient facilities in 3 different provinces in Austria. All consecutive patients aged ≥40 years with a diagnosis of COPD confirmed by a post-bronchodilator forced expired volume in 1 s/forced vital capacity (FEV

resultsAmong 283 patients fulfilling the inclusion criteria, 49.5% were considered non-exacerbators, 21.6% were classified as exacerbators with chronic bronchitis, 21.2% exacerbators without chronic bronchitis, and 7.8% were patients with an asthma-COPD overlap. Exacerbators had significantly higher prevalence of symptoms, lower lung function and exercise capacity, and a higher prevalence of comorbidities, such as heart failure and depression, compared with the other patient phenotypes. A large majority of patients with stable COPD in this cohort received inhaled triple therapy, irrespective of exacerbation history.

conclusionsThere were significant differences in COPD outcome measures between predefined phenotypes of COPD in this study. The majority of patients with stable COPD in this Austrian population were not treated according to current COPD guidelines. While non-exacerbators appear to have been overtreated, patients with an asthma-COPD overlap appear to have been undertreated.

Indexed as

PhenotypePulmonary Disease, Chronic ObstructiveAdministration, InhalationAgedAustriaBronchodilator AgentsCross-Sectional StudiesEurope, EasternFemaleHumansMaleMiddle AgedBronchodilator AgentsAsthmaCOPDExacerbationsLung functionPhenotypes

Identifiers

PMID29797071
OpenAlexW2804524174

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.