Evidence map›Paper›PMID 29797069›Full record

ArticleLung2018

Increased Airway Wall Thickness is Associated with Adverse Longitudinal First-Second Forced Expiratory Volume Trajectories of Former World Trade Center workers.

Rafael E de la Hoz, Xiaoyu Liu, John T Doucette, Anthony P Reeves, Laura A Bienenfeld, Juan P Wisnivesky, Juan C Celedón, David A Lynch, Raúl San José Estépar

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Lung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03295279 (Pulmonary Diseases in WTC Workers), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03295279 enrolling by invitationnot on this map

Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates

TypeobservationalSponsorIcahn School of Medicine at Mount SinaiRan2012 to 2027Enrolled2,122ConditionsChronic Airway Disease, Interstitial Lung Disease, Lung Cancer
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. COPD in Smoking and Non-Smoking Community Members Exposed to the World Trade Center Dust and Fumes.International journal of environmental research and public health · 2022
    Article
  4. Article
  5. Asthma-COPD overlap in World Trade Center Health Registry enrollees, 2015-2016.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rafael E de la HozDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Rafael.delaHoz@mssm.edu.ORCID http://orcid.org/0000-0002-8949-9279
Xiaoyu LiuDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-6528-0213
John T DoucetteDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-8985-0367
Anthony P ReevesSchool of Electrical and Computer Engineering, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0002-1451-3080
Laura A BienenfeldDepartment of Medicine, New York University School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-9252-8918
Juan P WisniveskyDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-0299-4582
Juan C CeledónDivision of Pediatric Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-6139-5320
David A LynchDepartment of Radiology, National Jewish Health, Denver, CO, USA.ORCID http://orcid.org/0000-0002-6329-2325
Raúl San José EstéparDepartment of Radiology, Brigham and Women's Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-3677-1996

Funding

Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT CorrelatesU01OH010401 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DE LA HOZ, RAFAEL E. · 2012 to 2025
$7.3M
Airway Inspector: a chest imaging biomarker software platform for COPDR01HL116931 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAN JOSE ESTEPAR, RAUL · 2013 to 2017
$2.2M
ACL HHS U01OH010401NHLBI NIH HHS R01 HL116931NIOSH CDC HHS U01 OH010401
6 · The paper itself

Abstract

rationaleOccupational exposures at the WTC site after September 11, 2001 have been associated with several presumably inflammatory lower airway diseases. In this study, we describe the trajectories of expiratory air flow decline, identify subgroups with adverse progression, and investigate the association of a quantitative computed tomography (QCT) imaging measurement of airway wall thickness, and other risk factors for adverse progression.

methodsWe examined the trajectories of expiratory air flow decline in a group of 799 former WTC workers and volunteers with QCT-measured (with two independent systems) wall area percent (WAP) and at least 3 periodic spirometries. We calculated individual regression lines for first-second forced expiratory volume (FEV

resultsThe mean longitudinal FEV

conclusionsThe apparent normal age-related rate of FEV

Indexed as

Airway RemodelingForced Expiratory VolumeOccupational HealthSeptember 11 Terrorist AttacksAdultAir Pollutants, OccupationalDisease ProgressionFemaleHumansJob DescriptionLungLung DiseasesMaleMiddle AgedMultidetector Computed TomographyOccupational ExposureAir Pollutants, Occupational2001Chronic bronchitisMultidetector computed tomographyOccupational diseaseSmoke inhalation injurySpirometryWorld Trade Center Attack

Identifiers

PMID29797069
PMCPMC6129294

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.