Evidence map›Paper›PMID 29796946›Full record

ArticlePlant cell reports2018

Comparative metabolomic responses to gibberellic acid and 6-benzylaminopurine in Cunila menthoides Benth. (Lamiaceae): a contribution to understand the metabolic pathways.

Joana P S Oliveira, Maria Gabriela B Koblitz, Mariana S L Ferreira, L C Cameron, Andrea F Macedo

Abstract read
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Article in Plant cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joana P S OliveiraIntegrated Laboratory of Plant Biology, Department of Botany, Institute of Biosciences, Federal University of Rio de Janeiro State, UNIRIO. Av. Pasteur, 458, Urca, Rio de Janeiro, 22290-240, Brazil.
Maria Gabriela B KoblitzLaboratory of Protein Biochemistry, Center of Innovation of Mass Spectrometry, Federal University of Rio de Janeiro State, UNIRIO. Av. Pasteur, 296, Urca, Rio de Janeiro, 22290-250, Brazil.
Mariana S L FerreiraLaboratory of Protein Biochemistry, Center of Innovation of Mass Spectrometry, Federal University of Rio de Janeiro State, UNIRIO. Av. Pasteur, 296, Urca, Rio de Janeiro, 22290-250, Brazil.
L C CameronLaboratory of Protein Biochemistry, Center of Innovation of Mass Spectrometry, Federal University of Rio de Janeiro State, UNIRIO. Av. Pasteur, 296, Urca, Rio de Janeiro, 22290-250, Brazil.
Andrea F MacedoIntegrated Laboratory of Plant Biology, Department of Botany, Institute of Biosciences, Federal University of Rio de Janeiro State, UNIRIO. Av. Pasteur, 458, Urca, Rio de Janeiro, 22290-240, Brazil. andreafm22@yahoo.com.br.
Universidade Federal do Rio de Janeiro · BRUniversidade Federal do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key messageGibberellic acid elicited synthesis of many phenols from different classes and enhanced production of sesquiterpenoids, polyterpenoids, steroids and monoterpenoids compared to control and 6-benzylaminopurine. Little is known about the effects of 6-benzylaminopurine (BA) and gibberellic acid (GA3) on the synthesis of secondary metabolites in species of Lamiaceae. In this study, for the first time, the profile of secondary metabolites in plantlets of Cunila menthoides was characterized, using UPLC-ESI-Qq-oaTOF-MS. Ninety metabolites were identified, including polyphenols and terpenes. BA down-regulated most of the identified molecules in relation to GA3 and MS0 (control). The results showed that GA3 elicited synthesis of many phenols from different classes, and seemed to play a major role in the shikimate pathway in relation to BA. GA3 enhanced production of sesquiterpenoids, polyterpenoids, steroids and monoterpenoids compared to MS0 and BA, and also seemed to positively influence the MEP/DOXP and MVA pathways. These data show the most comprehensive metabolomic profile of Cunila menthoides to date, and the effects of BA and GA3 on the synthesis of secondary metabolites, modulating quantitative aspects of metabolism in Lamiaceae.

Indexed as

Benzyl CompoundsGibberellinsLamiaceaeMetabolic Networks and PathwaysMetabolomicsPurinesbenzylaminopurineBenzyl Compoundsgibberellic acidGibberellinsPurinesGrowth regulatorsIn vitroLamiaceaeUntargeted metabolomicsUPLC-MS

Identifiers

PMID29796946
OpenAlexW2804159035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.