Evidence map›Paper›PMID 29796938›Full record

ArticleWorld journal of microbiology & biotechnology2018

The Rab GTPase activating protein Gyp2 contributes to UV stress tolerance in Metarhizium acridum.

Mushan Xie, Yuxian Xia, Yueqing Cao

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. AtGAP1 Promotes the Resistance toInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mushan XieSchool of Life Sciences, Chongqing University, Chongqing, 401331, People's Republic of China.
Yuxian XiaSchool of Life Sciences, Chongqing University, Chongqing, 401331, People's Republic of China.
Yueqing CaoSchool of Life Sciences, Chongqing University, Chongqing, 401331, People's Republic of China. yueqingcao@cqu.edu.cn.ORCID http://orcid.org/0000-0003-1903-8415
Chongqing University · CN

Funding

National Natural Science Foundation of China 31371992National Natural Science Foundation of China 31772222
6 · The paper itself

Abstract

GTPase activation protein (GAP) for Rab GTPases can accelerate GTP hydrolysis to alter the activity of Rab GTPases. To explore the function of GAP in entomopathogenic fungi, we constructed a deletion mutant of Gyp2 gene, a member of the Gyp (GAP for Ypt/Rab proteins) family in the locust-specific fungal pathogen, Metarhizium acridum. Results showed that the ∆MaGyp2 mutant had dramatically decreased tolerance to ultraviolet irradiation compared to wild type strain. Quantitative real-time PCR revealed that UV irradiation repair related genes Uve1 and WC1 were downregulated in ∆MaGyp2 mutant. Seven of other ten Gyp family members had significantly increased transcription in ∆MaGyp2 mutant compared with wild type, which may partly rescue the deficiency of MaGyp2.

Indexed as

Ultraviolet RaysAmino Acid SequenceAnimalsFungal ProteinsGene DeletionGene Expression Regulation, FungalGenes, FungalGrasshoppersGTPase-Activating ProteinsMetarhiziumRadiation ToleranceSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSequence Homology, Amino AcidStress, PsychologicalVirulenceFungal ProteinsGTPase-Activating ProteinsSaccharomyces cerevisiae ProteinsEntomopathogenic fungiGTPase activation proteinRab GTPaseUV irradiation tolerance

Identifiers

PMID29796938
OpenAlexW2804374589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.