Evidence map›Paper›PMID 29796913›Full record

Trial reportDigestive diseases and sciences2018

Angle of His Accentuation Is a Viable Alternative to Dor Fundoplication as an Adjunct to Laparoscopic Heller Cardiomyotomy: Results of a Randomized Clinical Study.

Prince Gupta, Rajinder Parshad, Pavithra Balakrishna, Anoop Saraya, Govind K Makharia, Sanjeev Sachdeva, Raju Sharma

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Fundoplication in laparoscopic Heller's cardiomyotomy for achalasia.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Article
  3. Article
  4. The Angle of His as a Measurable Element of the Anti-reflux Mechanism.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Prince GuptaDepartment of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), Delhi, India.
Rajinder ParshadDepartment of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), Delhi, India. drrajinderparshad.aiims@gmail.com.
Pavithra BalakrishnaDepartment of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), Delhi, India.
Anoop SarayaDepartment of Gastroenterology, All India Institute of Medical Sciences (AIIMS), Delhi, India.
Govind K MakhariaDepartment of Gastroenterology, All India Institute of Medical Sciences (AIIMS), Delhi, India.
Sanjeev SachdevaDepartment of Gastroenterology, G B Pant Hospital, Delhi, India.
Raju SharmaDepartment of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), Delhi, India.
All India Institute of Medical Sciences · INGovind Ballabh Pant Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is no consensus regarding the type of anti-reflux procedure to be used as an adjunct to laparoscopic Heller cardiomyotomy (LHCM). The aim of this study was to compare Angle of His accentuation (AOH) with Dor Fundoplication (Dor) as an adjunct to LHCM.

methodsA total of 110 patients with achalasia cardia presenting for LHCM from March 2010 to July 2015 were randomized to Dor and AOH. Symptom severity, achalasia-specific quality of life (ASQOL), new onset heartburn, and patient satisfaction were assessed using standardized scores preoperatively, at 3, 6 months, and then yearly. The primary outcome was relief of esophageal symptoms while secondary outcomes were new onset heartburn and ASQOL.

resultsBoth groups were comparable with respect to the baseline demographic characteristics. There was no conversion to open and no mortality in either group. Median operative time was 128 min in AOH and 144 min in Dor group (p < 0.01). Mean follow-up was 36 months and was available in 98% patients. There was significant improvement in esophageal symptoms in both groups with no statistically significant difference between the two groups (p > 0.05). There was no difference in cumulative symptom scores between the two groups over the period of follow-up. New onset heartburn was seen in 11% in AOH and 9% in Dor group. Mean ASQOL score improved in both groups with no difference between the two groups (p = 0.83). Patient satisfaction was similar in both groups.

conclusionAOH is similar to Dor as an adjunct to LHCM in safety and efficacy and can be performed in shorter time. CLINICAL REGISTRATION NUMBER: CTRI: REF/2014/06/007146.

Indexed as

AdolescentAdultAgedEsophageal AchalasiaFemaleFundoplicationHeartburnHeller MyotomyHumansIndiaMaleMiddle AgedOperative TimePatient SatisfactionQuality of LifeRecovery of FunctionAchalasiaAchalasia-specific quality of lifeAngle of his accentuationDor fundoplicationLaparoscopic Heller cardiomyotomy

Identifiers

PMID29796913
OpenAlexW2804344531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.