ArticleJournal of biomolecular NMR2018
Multiple frequency saturation pulses reduce CEST acquisition time for quantifying conformational exchange in biomolecules.
Article in Journal of biomolecular NMR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Two-dimensional NMR from a single pulse: Reconstructing heteronuclear 2D spectra via off-resonance decoupling and deep neural networks.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- NMR methods for investigating functionally relevant biomolecular dynamics.Magnetic resonance letters · 2025Review
- Article
- Studying micro to millisecond protein dynamics using simple amideJournal of biomolecular NMR · 2023Article
- Exploiting conformational dynamics to modulate the function of designed proteins.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Enzyme dynamics: Looking beyond a single structure.ChemCatChem · 2020Article
- A CEST NMR experiment to obtain glycineJournal of biomolecular NMR · 2020Article
- Extreme Nonuniform Sampling for Protein NMR Dynamics Studies in Minimal Time.Journal of the American Chemical Society · 2019Article
- Exchangeable deuterons introduce artifacts in amideJournal of biomolecular NMR · 2019Article
- Chemical Exchange.Methods in enzymology · 2019Article
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4 authors.
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Abstract
Exchange between conformational states is required for biomolecular catalysis, allostery, and folding. A variety of NMR experiments have been developed to quantify motional regimes ranging from nanoseconds to seconds. In this work, we describe an approach to speed up the acquisition of chemical exchange saturation transfer (CEST) experiments that are commonly used to probe millisecond to second conformational exchange in proteins and nucleic acids. The standard approach is to obtain CEST datasets through the acquisition of a series of 2D correlation spectra where each experiment utilizes a single saturation frequency to
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