Evidence map›Paper›PMID 29796738›Full record

ArticleInfection2018

HBV molecular epidemiology and clinical condition of immigrants living in Italy.

Caterina Sagnelli, Massimo Ciccozzi, Loredana Alessio, Eleonora Cella, Luciano Gualdieri, Mariantonietta Pisaturo, Carmine Minichini, Giovanni Di Caprio, Mario Starace, Lorenzo Onorato and 7 more

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Article in Infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Caterina SagnelliSection of Infectious Diseases, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Via L. Armanni 5, 80131, Naples, Italy.
Massimo CiccozziUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Rome, Italy.
Loredana AlessioMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Eleonora CellaUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Rome, Italy.
Luciano GualdieriMedical Center, Centro per la Tutela della Salute degli Immigrati, Naples, Italy.
Mariantonietta PisaturoMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Carmine MinichiniSection of Infectious Diseases, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Via L. Armanni 5, 80131, Naples, Italy.
Giovanni Di CaprioMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Mario StaraceSection of Infectious Diseases, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Via L. Armanni 5, 80131, Naples, Italy.
Lorenzo OnoratoMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Mara CapopreseMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Laura OcchielloMedical Center, Centro Sociale ex Canapificio, Caserta, Italy.
Silvia AngelettiUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Rome, Italy.
Gaetano ScottoInfectious Diseases Unit, Foggia, Italy.
Margherita MaceraSection of Infectious Diseases, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Via L. Armanni 5, 80131, Naples, Italy.
Evangelista SagnelliSection of Infectious Diseases, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Via L. Armanni 5, 80131, Naples, Italy. evangelista.sagnelli@unicampania.it.ORCID http://orcid.org/0000-0003-2817-8436
Nicola CoppolaSection of Infectious Diseases, Department of Mental Health and Public Medicine, University of Campania Luigi Vanvitelli, Via L. Armanni 5, 80131, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe investigated 170 HBsAg-positive immigrants living in Italy for 1-7 years to ascertain whether they may have become infected in the host country.

methodsOf 2032 adult immigrants interviewed, 1727 (85%) voluntarily adhered to a screening program for bloodborne or sexually transmitted infections. HBsAg was detected in 170 (9.8%) screened immigrants who completed the diagnostic, clinical and therapeutic process at the nearest clinic of infectious diseases. HBV molecular biology was performed applying a homemade technology. Phylogenetic signal of the datasets was obtained by a likelihood-mapping analysis using TreePuzzle.

resultsOf the 170 HBsAg-positive immigrants, 133 were inactive carriers, 29 had chronic hepatitis and 8 compensated cirrhosis. HBV genotype was identified in 109 of the 113 HBV-DNA-positive immigrants and HBV-genotype-E predominated (68.9%). Of these 109, 6 (5.5%) subjects showed an HBV genotype absent or extremely rare in their native country: HBV-genotype-E in three from Eastern Europe and in one from Sri Lanka, possibly acquired from other immigrants from sub-Saharan countries, HBV-genotype-D1 in one from Burkina Faso and one from Senegal, possibly acquired in Italy.

conclusionThe data suggest that immigrants may acquire HBV infection in Italy and, therefore, HBV vaccination programs should be extended to all immigrants living in Italy.

Indexed as

Emigrants and ImmigrantsAdultDNA, ViralFemaleGenetic VariationGenotypeHepatitis BHepatitis B, ChronicHepatitis B Surface AntigensHepatitis B virusHumansItalyMaleMolecular EpidemiologyPhylogenyPopulation SurveillanceDNA, ViralHepatitis B Surface AntigensChronic HBV infectionGenetic variabilityHBV genotypeHepatitis B virusPhenotypic variationRefugeesUndocumented immigrants

Identifiers

PMID29796738

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.