Evidence map›Paper›PMID 29796433›Full record

Observational studyRomanian journal of ophthalmology

Correlations between internal and external ocular factors and macular pigment optical density.

Ruxandra Tudosescu, Cristina Mihaela Alexandrescu, Sânziana Luminiţa Istrate, Alexandra Diana Vrapciu, Radu Constantin Ciuluvică, Liliana Voinea

Abstract readObservational Study
In one paragraph

Observational study in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruxandra TudosescuOphthalmology Department, "Regina Maria" Private Health Care Network, Dorobanţi Hyperclinic, Bucharest, Romania.
Cristina Mihaela AlexandrescuOphthalmology Department, University Emergency Hospital, Bucharest, Romania.
Sânziana Luminiţa IstrateOphthalmology Department, "Regina Maria" Private Health Care Network, Dorobanţi Hyperclinic, Bucharest, Romania.
Alexandra Diana VrapciuOphthalmology Department, University Emergency Hospital, Bucharest, Romania.
Radu Constantin CiuluvicăDivision of Anatomy, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Liliana VoineaOphthalmology Department, University Emergency Hospital, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the relationship between the macular pigment optical density and blue-light issued by computers, glare sensibility, with iris color, age, sex, or refractive errors. MATERIAL AND

methods83 patients (166 eyes) were enrolled in a prospective observational study. They were divided into 2 groups: group 1 (study group) - computer using patients (time spent in front of the computer for minimum 8 hours per day, 5 days per week, 2 years) - 43 patients and group 2 (control group) - 40 patients. The following investigations were conducted in all the selected cases: visual acuity, refraction, biomicroscopy, measurement of the MPOD, glare sensitivity, assessment of eye color.

results51.81% of the patients were included in group 1, while the rest, 48.19%, were in group 2. Thus, the MPOD had a mean value of (+/ -SD) 0.42+/ -0.13 (t = -1.08, p = 0.28) in group 1, and 0.44+/ -0.16 on the LE. The results showed a MPOD mean value of 0.51+/ - 0.16 in group 2 and 0.51+/ -0 .16. (t = 0.49, p = 0 .62) on the LE. 55.77% of the patients with light colored iris and 56.14% of those with dark iris had a low MPOD.

conclusionsThe data from our study failed to illustrate a significant correlation between MPOD and blue-light issued by computers. Furthermore, a statistic significant relationship regarding iris color, refractive errors, glare, and MPOD was not observed. ABBREVIATIONS: L = lutein, Z = zeaxanthin, MZ = meso-zeaxanthin, AMD = age related macular degeneration, MPOD = macular pigment optical density, MP = macular pigment, HFP = Heterochromatic Flicker Photometry, RE = right eye, LE = left eye.

Indexed as

Macular DegenerationMacular PigmentUser-Computer InterfaceVisual AcuityHumansLightLuteinProspective StudiesLuteinMacular Pigmentblue-lightcomputer using patientsiris colourmacular pigment optical densityrefractive erros

Identifiers

PMID29796433
PMCPMC5959024

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.