ReviewEye and vision (London, England)2018
Emerging Applications of Optical Coherence Tomography Angiography (OCTA) in neurological research.
Review in Eye and vision (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Pooled it
- Quantitative ophthalmic posterior segment optical coherence tomography angiography and neurologic conditions: a review.Frontiers in neurologyPooled it
- Vision-language semantic guidance and topology refinement for robust retinal vessel segmentation and biomarker analysis in cerebral small vessel disease.Frontiers in cell and developmental biology · 2026Article
- Ophthalmic, Systemic and Genetic Features in Wolfram Syndrome.Neuro-ophthalmology (Aeolus Press) · 2026Article
- Visual stimulus-evoked transient blood flow and blood vessel diameter changes in the healthy human retina measured with a combined OCT+ERG system.Biomedical optics express · 2025Article
- Combined optical coherence tomography and electroretinography system for imaging neurovascular coupling in the human retina.Neurophotonics · 2025Article
- Retinal Microstructural and Microvascular Changes in Alzheimer Disease: A Review.International ophthalmology clinics · 2025Review
- Early detection of dementia through retinal imaging and trustworthy AI.NPJ digital medicine · 2024Article
- Retinal Ischemic Perivascular Lesion Reflects Cerebral Small Vessel Disease Burden in Single Subcortical Infarction.Journal of the American Heart Association · 2024Article
- Insight into the Brain: Application of the Retinal Microvasculature as a Biomarker for Cerebrovascular Diseases through Optical Coherence Tomography Angiography.Current ophthalmology reports · 2024Article
- Article
- Evaluation of the Vascular Network with Optical Coherens Tomography Angiography in Multiple Sclerosis and its Relationship with the Clinic.Noro psikiyatri arsivi · 2024Article
- Effect of skin color on optical properties and the implications for medical optical technologies: a review.Journal of biomedical optics · 2024Review
- Relationship of retinal capillary plexus and ganglion cell complex with mild cognitive impairment and dementia.Eye (London, England) · 2023Article
- Review
- Retinal thickness and vascular parameters using optical coherence tomography in Alzheimer's disease: a meta-analysis.Neural regeneration research · 2023Article
- APOE ε4 Gene Carriers Demonstrate Reduced Retinal Capillary Densities in Asymptomatic Older Adults.Journal of clinical medicine · 2023Article
- Assessing the Sensitivity of OCT-A Retinal Vasculature Metrics.Translational vision science & technology · 2023Article
- Intrasession Repeatability of OCT Angiography Parameters in Neurodegenerative Disease.Ophthalmology science · 2023Article
- Central retinal microvasculature damage is associated with orthostatic hypotension in Parkinson's disease.NPJ Parkinson's disease · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo review the clinical and research value of optical coherence tomography angiography (OCTA) in the field of neurology.
methodsCurrent literature involving OCTA were reviewed through PubMed using the search terms "optical coherence tomography angiography", with "multiple sclerosis", "Alzheimer's disease", "optic neuropathy", or other closely-related terms.
resultsOCTA has been applied in research to advance our understanding of the pathobiology of neurological disorders. OCTA-derived blood flow and vessel density measures are altered in multiple sclerosis (MS), Alzheimer's disease (AD), and various optic neuropathies (ON) in varying regions of the posterior segment vasculature of the eye. These emerging research findings support the occurrence of retinal vascular alterations across a host of neurological disorders and raise the possibility that vasculopathy can be clinically relevant since it contributes to the pathobiology of several neurological disorders.
conclusionOCTA may be beneficial for neurological research. Additional investigations using OCTA in neurological disorders will help to further validate its clinical and research utilities in terms of characterizing the role of vasculopathy in neurological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.