Evidence map›Paper›PMID 29796316›Full record

ArticleInternational journal of vascular medicine2018

Effect of N-Acetylcysteine on Dyslipidemia and Carbohydrate Metabolism in STZ-Induced Diabetic Rats.

Anderson Kiyoshi Kaga, Pedro Octavio Barbanera, Nágilla Orleanne Lima do Carmo, Lucas Rodolfo de Oliveira Rosa, Ana Angélica Henrique Fernandes

Open access · goldAbstract read
In one paragraph

Article in International journal of vascular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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  9. Toxicology reports · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anderson Kiyoshi KagaDepartment of Chemistry and Biochemistry, Institute of Biosciences of Botucatu, Sao Paulo State University (UNESP), Rua Professor Doutor Antônio Celso Wagner Zanin s/n, Distrito de Rubião Júnior, 18618-689 Botucatu, SP, Brazil.ORCID 0000-0003-3948-5757
Pedro Octavio BarbaneraDepartment of Chemistry and Biochemistry, Institute of Biosciences of Botucatu, Sao Paulo State University (UNESP), Rua Professor Doutor Antônio Celso Wagner Zanin s/n, Distrito de Rubião Júnior, 18618-689 Botucatu, SP, Brazil.
Nágilla Orleanne Lima do CarmoDepartment of Chemistry and Biochemistry, Institute of Biosciences of Botucatu, Sao Paulo State University (UNESP), Rua Professor Doutor Antônio Celso Wagner Zanin s/n, Distrito de Rubião Júnior, 18618-689 Botucatu, SP, Brazil.
Lucas Rodolfo de Oliveira RosaDepartment of Chemistry and Biochemistry, Institute of Biosciences of Botucatu, Sao Paulo State University (UNESP), Rua Professor Doutor Antônio Celso Wagner Zanin s/n, Distrito de Rubião Júnior, 18618-689 Botucatu, SP, Brazil.ORCID 0000-0001-8757-6165
Ana Angélica Henrique FernandesDepartment of Chemistry and Biochemistry, Institute of Biosciences of Botucatu, Sao Paulo State University (UNESP), Rua Professor Doutor Antônio Celso Wagner Zanin s/n, Distrito de Rubião Júnior, 18618-689 Botucatu, SP, Brazil.ORCID 0000-0002-7170-182X
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 1 diabetes mellitus (T1DM) is characterized by insulin-deficient production leading to hyperglycemia, which is associated with diabetic complications such as cardiovascular diseases. Antioxidants have been proving a good alternative to diabetic complications, with N-acetylcysteine (NAC) having antioxidant characteristics. The aim of this study was to assess the effect of NAC on the lipid profile and the atherogenic index (AI) in streptozotocin- (STZ-) induced diabetic rats.

method32 male Wistar rats (60 days of age) weighting ±250 g were randomly distributed into four groups (

resultsNAC decreased (

conclusionNAC improves lipid profile and decreases AI in STZ-induced diabetic rats.

Identifiers

PMID29796316
PMCPMC5896413
OpenAlexW2786527888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.