Evidence map›Paper›PMID 29796276›Full record

ArticleRespirology case reports2018

Successful treatment by tolvaptan of the syndrome of inappropriate antidiuretic hormone secretion that may be associated with chemotherapy-induced tumour lysis in a patient with small-cell lung carcinoma.

Koichi Miyashita, Shun Matsuura, Hyogo Naoi, Masaru Tsukui, Naoki Koshimizu, Takafumi Suda

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Koichi MiyashitaDepartment of Respiratory Medicine Fujieda Municipal General Hospital Fujieda Japan.ORCID 0000-0003-3550-1182
Shun MatsuuraDepartment of Respiratory Medicine Fujieda Municipal General Hospital Fujieda Japan.
Hyogo NaoiDepartment of Respiratory Medicine Fujieda Municipal General Hospital Fujieda Japan.
Masaru TsukuiDepartment of Respiratory Medicine Fujieda Municipal General Hospital Fujieda Japan.
Naoki KoshimizuDepartment of Respiratory Medicine Fujieda Municipal General Hospital Fujieda Japan.
Takafumi SudaSecond Division, Department of Internal Medicine Hamamatsu University School of Medicine Hamamatsu Japan.
Fujieda Municipal General Hospital · JPHamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report the case of a patient with small-cell lung carcinoma (SCLC) who developed the syndrome of inappropriate antidiuretic hormone secretion (SIADH). This syndrome may be associated with chemotherapy-induced tumour lysis. Our patient was successfully treated with tolvaptan. A 70-year-old man was diagnosed with SCLC and was treated with carboplatin and etoposide. Episodes of hyponatremia occurred after every four cycles of chemotherapy that achieved tumour reduction; however, the hyponatremia was improved by temporary administration of tolvaptan. In SIADH associated with chemotherapy-induced tumour lysis, tolvaptan may improve hyponatremia and enable the continued administration of effective chemotherapy.

Indexed as

small‐cell lung carcinomasyndrome of inappropriate antidiuretic hormone secretiontolvaptantumour lysis

Identifiers

PMID29796276
PMCPMC5961507
OpenAlexW2791950056

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.