Evidence map›Paper›PMID 29796221›Full record

ArticleIranian journal of basic medical sciences2018

Can crocin play a preventive role in Wistar rats with carbon tetrachloride-induced nephrotoxicity?

Mehmet Erman Erdemli, Mehmet Gul, Eyup Altinoz, Zeynep Aksungur, Semir Gul, Harika Gozukara Bag

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mehmet Erman ErdemliDepartment of Medical Biochemistry, Medical Faculty, Nigde Omer Halisdemir University, Nigde, Turkey.
Mehmet GulDepartment of Histology and Embryology, Medical Faculty, Inonu University, Malatya, Turkey.
Eyup AltinozDepartment of Medical Biochemistry, Medical Faculty, Karabuk University, Karabuk, Turkey.
Zeynep AksungurDepartment of Medical Biochemistry, Medical Faculty, Inonu University, Malatya, Turkey.
Semir GulDepartment of Histology and Embryology, Medical Faculty, Inonu University, Malatya, Turkey.
Harika Gozukara BagDepartment of Biostatistics, Medical Faculty, Inonu University, Malatya, Turkey.
Inonu University · TRKarabük University · TRNiğde Ömer Halisdemir Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate protective role of crocin by attempting to create nephrotoxicity with carbon tetrachloride. MATERIALS AND

methodsEthics committee approval was obtained and 50 male Wistar rats were randomly divided into 5 groups that included 10 rats each: Control, Corn oil, Crocin, Carbon tetrachloride (CCl4), and Crocin + Carbon tetrachloride. Following the experiments, the rats were decapitated under anesthesia and incised kidney tissues were subjected to biochemical and histological examinations.

resultsIn the CCl

conclusionAt this dose and time interval, against a highly toxic chemical such as CCl

Indexed as

Carbon tetrachlorideCrocinKidneyOxidative stressRat

Identifiers

PMID29796221
PMCPMC5960754
OpenAlexW2789039562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.