Evidence map›Paper›PMID 29796180›Full record

ArticleOncotarget2018

Gene expression profiling in prognosis of distant recurrence in HR-positive and HER2-negative breast cancer patients.

Tzu-Ting Huang, Nicolas Pennarun, Yu-Hao Cheng, Cheng-Fang Horng, Jason Lei, Skye Hung-Chun Cheng

Registry-linked trialAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04069884 (RecurIndex Guided Avoidance of Regional Nodal Irradiation for Node Positive Breast Cancer), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04069884 narecruitingnot on this mapstarted 2019, after this paper: background citation

RecurIndex Guided Avoidance of Regional Nodal Irradiation for Node Positive Breast Cancer

TypeinterventionalSponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityRan2019 to 2030Enrolled540ConditionsBreast Cancer, RadiationArmsregional nodal irradiation, WBI, chestwall XRT
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Breast cancer gene expression signatures: development and clinical significance-a narrative review.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tzu-Ting HuangDepartment of Medical Research, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Nicolas PennarunDepartment of Medical Research, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Yu-Hao ChengDepartment of Medicine, Cathy General Hospital, Taipei, Taiwan.
Cheng-Fang HorngDepartment of Medical Research, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Jason LeiDepartment of Product Development, Amwise Diagnostics Pte Ltd, Taipei, Taiwan.
Skye Hung-Chun ChengDepartment of Medical Research, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There had been several studies using gene-expression profiling in predicting distant recurrence in breast cancer. In this study, we developed an 18-gene classifier (18-GC) to predict distant recurrence of breast cancer and compared it with the 21-gene panel (Oncotype DX

Indexed as

breast cancerchemotherapydistant recurrence predictiongene expression profilingmicroarray

Identifiers

PMID29796180
PMCPMC5955427

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.