ArticleNeuropsychiatric disease and treatment2018
Disrupted interhemispheric functional connectivity in chronic insomnia disorder: a resting-state fMRI study.
Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Trial
- State-specific thalamic dysregulation in chronic insomnia revealed by dynamic edge-centric functional connectivity.Scientific reports · 2025Article
- Insomnia and stress: the mediating roles of frontoparietal network.Brain imaging and behavior · 2024Article
- Multimodal transformer graph convolution attention isomorphism network (MTCGAIN): a novel deep network for detection of insomnia disorder.Quantitative imaging in medicine and surgery · 2024Article
- Article
- Impaired interhemispheric synchrony in patients with iridocyclitis and classification using machine learning: an fMRI study.Frontiers in immunology · 2024Article
- Dysfunction in the Interaction of Information Between and Within the Bilateral Primary Sensory Cortex.Frontiers in aging neuroscience · 2022Article
- Improved Regional Homogeneity in Chronic Insomnia Disorder After Amygdala-Based Real-Time fMRI Neurofeedback Training.Frontiers in psychiatry · 2022Article
- Connectomic disturbances underlying insomnia disorder and predictors of treatment response.Frontiers in human neuroscience · 2022Article
- Common and distinct brain functional alterations in pharmacotherapy treatment-naïve female borderline personality disorder patients with and without auditory verbal hallucinations: a pilot study.European archives of psychiatry and clinical neuroscience · 2021Article
- Impaired Interhemispheric Synchrony in Bronchial Asthma.International journal of general medicine · 2021Article
- Treatment of auditory verbal hallucinations with atypical antipsychotics in healthy individuals: an artificially controlled post-treatment report.The Journal of international medical research · 2020Article
- Alterations of Interhemispheric Functional Connectivity in Parkinson's Disease With Depression: A Resting-State Functional MRI Study.Frontiers in human neuroscience · 2020Article
- Using Nonlinear Dynamics and Multivariate Statistics to Analyze EEG Signals of Insomniacs with the Intervention of Superficial Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Reduced Interhemispheric Functional Connectivity in Obsessive-Compulsive Disorder Patients.Frontiers in psychiatry · 2019Article
- Altered Default Mode and Sensorimotor Network Connectivity With Striatal Subregions in Primary Insomnia: A Resting-State Multi-Band fMRI Study.Frontiers in neuroscience · 2018Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAbnormalities in both cerebral structure and intrinsic activity have been increasingly reported in patients with chronic insomnia disorder (CID). However, the inter-hemispheric integration function in CID is still not well understood. Functional homotopy reflects an essential aspect of the intrinsic functional architecture involved in interhemispheric coordination.
methodsIn this study, voxel-mirrored homotopic connectivity (VMHC) was used to analyze the patterns of interhemispheric intrinsic functional connectivity in patients with CID (n=29).
resultsReduced homotopic connectivity was observed in the middle occipital/posterior middle temporal gyrus in CID patients relative to control subjects. Further analyses demonstrated different insomnia-related heterotopic connectivity patterns in the right and left middle occipital/posterior middle temporal gyrus. Furthermore, within the CID group, the connectivity coefficient within the connectivity network of the middle occipital/posterior middle temporal gyrus was associated with anxiety measures.
conclusionNegative significant findings of group differences were found in terms of both the local gray matter density and fractional anisotropy of the white matter skeletal measures in this study; this structural finding, together with the results of VMHC, suggested that disruptions in the intrinsic functional architecture of interhemispheric communication associated with CID can be observed in the absence of detectable microstructural or local morphometric changes in white and gray matter.
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