ArticlePloS one2018
Neonatal and maternal serum creatinine levels during the early postnatal period in preterm and term infants.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- The Impact of Erythropoietin on Short- and Long-Term Kidney-Related Outcomes in Neonates of Extremely Low Gestational Age. Results of a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial.The Journal of pediatrics · 2021Trial
- Prevalence of acute kidney injury (AKI) in extremely low gestational age neonates (ELGAN).Pediatric nephrology (Berlin, Germany) · 2020Trial
- Improving pediatric post-acute kidney injury care: considerations for the clinician.Renal failure · 2026Review
- From Gestational Age-Specific Serum Creatinine Trajectories to an Interactive Clinical Interpretation Tool in Level IV NICU Infants.Research square · 2026Article
- Comparison of creatinine- and cystatin C-based definitions of acute kidney injury in neonates with congenital diaphragmatic hernia.Pediatric nephrology (Berlin, Germany) · 2026Observational
- The early predictive value of Cys-C, lactic acid, and urinary microglobulins in acute kidney injury following neonatal asphyxia.Translational pediatrics · 2026Article
- Impact of Postnatal Changes in Creatinine Levels on Plasma Gentamicin Concentrations in Neonates.Pharmaceutical research · 2026Observational
- Evolutionary digital twin framework for optimal aminoglycoside dosing in neonates with suspected sepsis.NPJ digital medicine · 2026Article
- Biomarker urinary neutrophil gelatinase-associated lipocalin as a predictor of acute kidney injury in neonates.Future science OA · 2025Article
- Article
- Follow-up of congenital abnormalities of the kidney and urinary tract from the antenatal period to the first year of life: a retrospective study from Turkey.Childhood kidney diseases · 2025Article
- Amikacin dosing in neonates: evaluation of target attainment using a simplified and complex pharmacokinetic model-derived dosing regimen in clinical practice.Antimicrobial agents and chemotherapy · 2025Article
- Neonatal Kidney Function, Injury and Drug Dosing: A Contemporary Review.Children (Basel, Switzerland) · 2025Review
- A Pooled Population Pharmacokinetic Study of Oral and Intravenous Administration of Clavulanic Acid in Neonates and Infants: Targeting Effective Beta-Lactamase Inhibition.Clinical pharmacology and therapeutics · 2025Article
- The Prognostic Value of Serum Creatinine Dynamics in Neonates-A Retrospective Cohort Study.Journal of clinical medicine · 2024Article
- External evaluation of neonatal vancomycin population pharmacokinetic models: Moving from first-order equations to Bayesian-guided therapeutic monitoring.Pharmacotherapy · 2024Article
- A mechanistic reflection on the relationship between maternal and neonatal serum creatinine values at delivery.Clinical and experimental nephrology · 2024Article
- Cardiac Dysfunction Associated with Lacosamide in a Premature Infant with Hypoxic Ischemic Encephalopathy: A Case Report.AJP reports · 2024Article
- Ototoxic and nephrotoxic drugs in neonatal intensive care units: results of a Spanish and Italian survey.European journal of pediatrics · 2024Article
- Relationship between the serum creatinine concentrations of preterm neonates within 24 h of birth and their mothers before delivery.Clinical and experimental nephrology · 2024Article
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Authors and funding
10 authors.
Funding
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Abstract
We investigated the relationship of neonatal and maternal serum creatinine (nSCr and mSCr, respectively) with various maternal/infant characteristics at different gestational ages (GA). We reviewed medical records of neonates admitted to NICU. We collected data on birth weight, GA, Apgar scores, medications, etc. Spearman's test was used to analyze the correlation between serum creatinine and continuous variables, and the Mann-Whitney U and Kruskal-Wallis tests for continuous variables between groups. The changes in nSCr, mSCr, and nSCr/mSCr ratio because of gestational age and the points in gestational changes in trends were estimated using joinpoint trend analysis. From 614 neonate and mother pairs, we found that nSCr was significantly correlated with GA. However, mSCr at >28 wks decreased with GA. The nSCr/mSCr ratio was correlated with GA. In infants born <29 weeks, pregnancy-induced hypertension (PIH) (p = 0.000, β = 0.20) and mSCr (p = 0.000, β = 0.73) were significantly associated with nSCr. In term infants, maternal magnesium administration (p = 0.000, β = 0.25), respiratory distress syndrome (p = 0.013, β = 0.16), PIH (p = 0.005, β = 0.19), and mSCr (p = 0.000, β = 0.33) were significantly associated with nSCr. nSCr reflected mSCr at all gestational ages. The correlation between nSCr and mSCr in preterm infants (p = 0.000, β = 0.74) was stronger than in term infants (p = 0.000, β = 0.34).
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