Evidence map›Paper›PMID 29795528›Full record

SynthesisInternational journal of impotence research2018

Association between obstructive sleep apnea and erectile dysfunction: a systematic review and meta-analysis.

S V Kellesarian, V R Malignaggi, C Feng, F Javed

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of impotence research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Review
  8. The Global Burden of Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2025
    Review
  9. Review
  10. Approach the Patient With Obstructive Sleep Apnea and Obesity.The Journal of clinical endocrinology and metabolism · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. A Review of a Recent Meta-Analysis Study on Obstructive Sleep Apnea.Journal of rhinology : official journal of the Korean Rhinologic Society · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

S V KellesarianDepartment of General Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA. sergio_kellesarian@urmc.rochester.edu.ORCID http://orcid.org/0000-0002-0760-841X
V R MalignaggiDepartment of General Dentistry, Faculty of Dentistry, Universidad Santa Maria, Caracas, Venezuela.
C FengDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, NY, USA.
F JavedDepartment of General Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
Eastman Chemical Company (United States) · USUniversidad Santa María · VEUniversity of Rochester · USUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the present systematic review and meta-analysis was to assess the association between obstructive sleep apnea (OSA) and erectile dysfunction (ED). To address the focused question, "Is there an association between OSA and ED?" indexed databases were searched up to May 2017 without time or language restrictions using various key words including: obstructive sleep apnea, sleep apnea syndromes, erectile dysfunction, sleep-disordered breathing, snoring, sexual function, and impotence. Review articles, case-reports and case-series, commentaries, letters to the editor, interviews and updates, studies assessing the efficacy of OSA treatment in the improvement of ED, or studies evaluating the efficacy of ED treatment in the improvement of OSA were excluded. Twenty-eight observational studies were included for qualitative synthesis. Overall, 19 studies had a cross-sectional design, 7 studies were case-control, and 2 were cohort studies. The odds ratios (OR) with a 95% confidence interval were calculated from 10 studies. The combined OR was 0.45, with a 95% confidence interval of 0.18-0.71, indicating that in patients without OSA, the risk of ED is significantly lower compared with patients with OSA. The available evidence shows that OSA is associated with a higher risk of ED; however, further well-designed controlled clinical trials and longitudinal prospective studies are needed in this regard.

Indexed as

Erectile DysfunctionHumansMalePolysomnographyRisk FactorsSleepSleep Apnea, Obstructive

Identifiers

PMID29795528
OpenAlexW2804934005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.