ArticleInternational journal of obesity (2005)2018
Maternal obesity aggravates the abnormality of porcine placenta by increasing N
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 48 citations in OpenAlex.
- Impact of Feed Intake and Body Fat Deposition on Reproductive Performance and Placental Function of Shaziling Sows: A Pilot Study.Animals : an open access journal from MDPI · 2026Article
- Excess backfat deposition and restricted feeding in gestating sows: An overview of mechanisms compromising their health and performance, and regulatory effects of functional dietary fibers.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- Effect of fat deposition on placental function in Shaziling sows and modulation by resveratrol.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- LncRNA GAS5 Regulates Myometrial Cell Contractions in an m6A-Dependent Manner.Function (Oxford, England) · 2025Article
- Epigenetic regulation in oogenesis and fetal development: insights into m6A modifications.Frontiers in immunology · 2025Review
- Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus.iScience · 2024Article
- Abnormal adipose tissue-derived microbes drive metabolic disorder and exacerbate postnatal growth retardation in piglet.Life metabolism · 2024Article
- RNA NCell communication and signaling : CCS · 2023Review
- Placental Malfunction, Fetal Survival and Development Caused by Sow Metabolic Disorder: The Impact of Maternal Oxidative Stress.Antioxidants (Basel, Switzerland) · 2023Review
- N6-methyladenosine modifications in maternal-fetal crosstalk and gestational diseases.Frontiers in cell and developmental biology · 2023Review
- Diallyl Trisulfide Promotes Placental Angiogenesis by Regulating Lipid Metabolism and Alleviating Inflammatory Responses in Obese Pregnant Mice.Nutrients · 2022Article
- Gene model-related m6A expression levels predict the risk of preeclampsia.BMC medical genomics · 2022Article
- Maternal obesity inhibits placental angiogenesis by down-regulating the SIRT1/PGC-1α pathway.Annals of translational medicine · 2022Article
- Fear Stress During Pregnancy Affects Placental m6A-Modifying Enzyme Expression and Epigenetic Modification Levels.Frontiers in genetics · 2022Article
- Effects on the Cell Barrier Function of L-Met and DL-HMTBA Is Related to Metabolic Characteristics and mFrontiers in nutrition · 2022Article
- Association between the levels of CGI-58 and lipoprotein lipase in the placenta of patients with preeclampsia.Experimental and therapeutic medicine · 2021Article
- Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway.Redox biology · 2021Article
- Effect of gestation dietary methionine-to-lysine ratio on methionine metabolism and antioxidant ability of high-prolific sows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- RNA methylation and neurovascular unit remodeling.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Maternal Obesity Increases Oxidative Stress in Placenta and It Is Associated With Intestinal Microbiota.Frontiers in cellular and infection microbiology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe growing prevalence of overweight or obese pregnancies shows an increasing risk for aberrant fetal growth and postnatal complications. Maternal obesity is associated with low birth weight (LBW) of piglets. However, the development of LBW from maternal obesity is not well understood.
objectiveThis study attempts to investigate the novel RNA modification N6-methyladenosine (m SUBJECTS/
methodsForty four placentas from eight sows (backfat thickness ≥21 mm) were divided into four groups by piglet weight, with group1 being LBW group (<1.0 kg), group2 (1.0-1.4 kg), group3 (1.4-1.6 kg), and group4 (>1.6 kg) as the comparative groups of normal birth weight. QPCR was used to measure the mRNA levels of the genes and western blot was used to test the content of proteins. At the same time, LC-MS/MS method was built to test the content of m
resultsCompared with the comparative groups, the expression levels of PPARγ, VEGFA, ABHD5, and GPR120 in both mRNA and protein decreased noticeably in the LBW group. It was also observed that the density of the H&E stained vessels became attenuated in LBW group. Importantly, for the first time, the increased m
conclusionWe infer that in maternity obesity, the higher m
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.