Evidence map›Paper›PMID 29795453›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

NICU management and outcomes of infants with trisomy 21 without major anomalies.

Sarah McAndrew, Krishna Acharya, T Hang Nghiem-Rao, Steven Leuthner, Reese Clark, Joanne Lagatta

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Morbidity and mortality in neonates with Down Syndrome based on gestational age.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  5. Review
  6. Article
  7. Temperature instability in infants with trisomy 21 in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
  8. Cardiac mechanics in infants with Down syndrome in the early neonatal period.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah McAndrewDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Krishna AcharyaDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
T Hang Nghiem-RaoDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Steven LeuthnerDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Reese ClarkPediatrix Medical Group, Sunrise, FL, USA.
Joanne LagattaDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA. jlagatta@mcw.edu.

Funding

Role of Prematurity and Sterol Metabolism in Parenteral Nutrition-Associated Liver DiseaseK23DK109071 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI NGHIEM-RAO, TUYET-HANG · 2017 to 2021
$949k
NIDDK NIH HHS K23 DK109071
6 · The paper itself

Abstract

objectiveTo describe how trisomy 21 affects neonatal intensive care management and outcomes of full-term infants without congenital anomalies. STUDY

designRetrospective cohort of full-term infants without anomalies with and without trisomy 21 admitted to Pediatrix NICUs from 2005 to 2012. We compared diagnoses, management, length of stay, and discharge outcomes.

resultsIn all, 4623 infants with trisomy 21 and 606 770 infants without trisomy 21 were identified. One-third of infants in the NICU with and without trisomy 21 were full term without major anomalies. Trisomy 21 infants had more respiratory distress, thrombocytopenia, feeding problems, and pulmonary hypertension. They received respiratory support for a longer period of time and had a longer length of stay.

conclusionOne-third of infants with trisomy 21 admitted to the NICU are full term without major anomalies. Common diagnoses and greater respiratory needs place infants with trisomy 21 at risk for longer length of stay.

Indexed as

Birth WeightDown SyndromeFeeding BehaviorFemaleHumansHypertension, PulmonaryInfant, NewbornIntensive Care, NeonatalIntensive Care Units, NeonatalLength of StayLinear ModelsMaleMultivariate AnalysisRespiratory Distress Syndrome, NewbornRetrospective StudiesThrombocytopenia

Identifiers

PMID29795453
PMCPMC6335104

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.