Evidence map›Paper›PMID 29795436›Full record

SynthesisBone marrow transplantation2018

Impact of body mass index at different transplantation stages on postoperative outcomes in patients with hematological malignancies: a meta-analysis.

Guangxu Ren, Wei Cai, Liping Wang, Jiazhang Huang, Suqin Yi, Lingang Lu, Jing Wang

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Nutritional status and body mass index before hematopoietic stem cell transplantation (HSCT) and associated outcomes: a rapid review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guangxu RenInstitute of Food and Nutrition Development, Ministry of Agriculture, 100081, Beijing, China. renguangxu@caas.cn.
Wei CaiQinhai University Affiliated Hospital, 810001, Xining, China.
Liping WangInstitute of Food and Nutrition Development, Ministry of Agriculture, 100081, Beijing, China.
Jiazhang HuangInstitute of Food and Nutrition Development, Ministry of Agriculture, 100081, Beijing, China.
Suqin YiInstitute of Food and Nutrition Development, Ministry of Agriculture, 100081, Beijing, China.
Lingang LuInstitute of Food and Nutrition Development, Ministry of Agriculture, 100081, Beijing, China.
Jing WangInstitute of Food and Nutrition Development, Ministry of Agriculture, 100081, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the association between body mass index (BMI) and overall survival (OS) has been reported in leukemia patients of different ages, whether BMI levels at different stages of hematopoietic stem cell transplantation (HSCT) have different effects on postoperative survival remains controversial. We searched four electronic databases from inception through July 2017 without any language restrictions and included studies on different types of hematological malignancies reporting both BMI time points and HSCT. Of the 1420 articles identified, 26 articles were eligible for inclusion in this meta-analysis. Three weight groups (obese, overweight and underweight) were individually compared with the normal group. Summary risk estimates for OS and event-free survival (EFS) were calculated with random- or fixed-effects models. For BMI at the pre-HSCT stage, a statistically significant positive association of increased risk of OS (RR: 1.17; 95% CI: 1.08-1.27) and EFS (RR: 1.29; 95% CI: 1-1.67) was identified in underweight individuals compared with those with normal weights. For BMI in the HSCT stage, a lower BMI was significantly associated with poorer OS (RR: 1.34; 95% CI: 1.01-1.78) and EFS (RR: 1.53; 95% CI: 1.09-2.06) compared with a normal BMI. Our results indicated that lower BMI at the pre-HSCT stage or during HSCT is associated with poorer survival.

Indexed as

Body Mass IndexAdultAgedFemaleHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedPostoperative ComplicationsTransplantation ConditioningYoung Adult

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.