Evidence map›Paper›PMID 29795426›Full record

ReviewBone marrow transplantation2019

Prevention and treatment of relapse after stem cell transplantation by cellular therapies.

Fred Falkenburg, Eliana Ruggiero, Chaira Bonini, David Porter, Jeff Miller, Floran Malard, Mohamad Mohty, Nicolaus Kröger, Hans Jochem Kolb

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Increasing Role of Targeted Immunotherapies in the Treatment of AML.International journal of molecular sciences · 2022
    Review
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Fred FalkenburgDepartment of Hematology, Leiden University Medical Center, Leiden, Netherlands.
Eliana RuggieroExperimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.
Chaira BoniniExperimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy.
David PorterDivision of Hematology/Oncology, Blood and Marrow Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jeff MillerBlood and Marrow Transplant Program, University of Minnesota, Minneapolis, USA.
Floran MalardHematology Department, AP-HP, Saint Antoine Hospital, Paris, France.
Mohamad MohtyHematology Department, AP-HP, Saint Antoine Hospital, Paris, France.
Nicolaus KrögerDepartment of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. nkroeger@uke.uni-hamburg.de.
Hans Jochem KolbKolb Consulting, München, Germany.
Vita-Salute San Raffaele University · ITHôpital Saint-Antoine · FRLeiden University Medical Center · NLSorbonne Université · FRUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Minnesota · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in reducing therapy-related mortality after allogeneic stem cell transplantation (alloSCT) relapse remains the major cause of treatment failure and little progress has been achieved in the last decades. At the 3rd International Workshop on Biology, Prevention, and Treatment of Relapse held in Hamburg/Germany in November 2016 international experts presented and discussed recent developments in the field. Here, the potential of cellular therapies including unspecific and specific T cells, genetically modified T cells, CAR-T cells, NK-cells, and second allografting in prevention and treatment of relapse after alloSCT are summarized.

Indexed as

Immunotherapy, AdoptiveStem Cell TransplantationAllograftsHumansKiller Cells, NaturalRecurrenceT-Lymphocytes

Identifiers

PMID29795426
OpenAlexW2803708076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.