Evidence map›Paper›PMID 29795357›Full record

ArticleActa pharmacologica Sinica2018

Pharmacological and functional comparisons of α6/α3β2β3-nAChRs and α4β2-nAChRs heterologously expressed in the human epithelial SH-EP1 cell line.

De-Jie Chen, Fen-Fei Gao, Xiao-Kuang Ma, Gang-Gang Shi, Yuan-Bing Huang, Quang-Xi Su, Sterling Sudweeks, Ming Gao, Turner Dharshaun, Jason Brek Eaton and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Cocaine potently blocks neuronal αActa pharmacologica Sinica · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

De-Jie ChenDepartment of Neurology, Yunfu People's Hospital, Yunfu, 527300, China.
Fen-Fei GaoDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Xiao-Kuang MaDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Gang-Gang ShiDepartment of Pharmacology, Shantou University Medical College, Shantou, 515063, China.
Yuan-Bing HuangDepartment of Neurology, Yunfu People's Hospital, Yunfu, 527300, China.
Quang-Xi SuDepartment of Neurology, Yunfu People's Hospital, Yunfu, 527300, China.
Sterling SudweeksDepartments of Psychology and Developmental Biology, Brigham Young University, Provo, UT, 84602, USA.
Ming GaoDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Turner DharshaunDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Jason Brek EatonDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Yong-Chang ChangDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
J Michael McintoshGeorge E Wahlen Veterans Affairs Medical Center, Salt Lake City, UT, 84108, USA.
Ronald J LukasDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Paul WhiteakerDepartment of Neurobiology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, 85013, USA.
Scott C SteffensenDepartment of Physiology and Neuroscience, Brigham Young University, Provo, UT, 84602, USA.
Jie WuDepartment of Neurology, Yunfu People's Hospital, Yunfu, 527300, China. jie.wu@DignityHealth.org.
St. Joseph's Hospital and Medical Center · USBarrow Neurological Institute · USBrigham Young University · USRuian People's Hospital · CNShantou University · CNShantou University Medical College · CNUniversity of Utah · US

Funding

Venoms, Biological Resources, Molecular BiologyP01GM048677 · NIGMS · UNIVERSITY OF UTAH · PI OLIVERA, BALDOMERO M · 1993 to 2018
$32.2M
Relevance of α-Conotoxin MII Sensitive Nicotinic Receptor Subtypes to Nicotine AddictionR01DA042749 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WHITEAKER, PAUL · 2017 to 2021
$2.8M
Novel nAChR-Targeted PeptidesR01GM103801 · NIGMS · UNIVERSITY OF UTAH · PI MCINTOSH, J MICHAEL · 2012 to 2019
$2.4M
Nicotine and Alcohol Co-DependenceR01DA035958 · NIDA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2014 to 2018
$2.0M
Construction and Expression of Concatemeric alpha6beta2* Nicotinic Acetycholine RR21DA026627 · NIDA · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI WHITEAKER, PAUL · 2009 to 2010
$407k
NIDA NIH HHS R01 DA035958NIDA NIH HHS R01 DA042749NIDA NIH HHS R21 DA026627NIGMS NIH HHS P01 GM048677NIGMS NIH HHS R01 GM103801
6 · The paper itself

Abstract

Neuronal nicotinic acetylcholine receptors containing α6 subunits (α6

Indexed as

Amino Acid SequenceCell LineHumansKineticsNicotinic AgonistsNicotinic AntagonistsPatch-Clamp TechniquesReceptors, NicotinicNicotinic AgonistsNicotinic Antagonistsnicotinic receptor alpha4beta2nicotinic receptor alpha6Receptors, Nicotinicacetylcholinenicotinenicotinic acetylcholine receptorpatch-clampSH-EP1 cells

Identifiers

PMID29795357
PMCPMC6289390
OpenAlexW2803389286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.