ArticleNature2018
Reconstruction of antibody dynamics and infection histories to evaluate dengue risk.
Abstract read
In one paragraph
Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 202 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
202 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity.Nature communications · 2020Pooled it
- Trial
- Analysis of Neutralizing Antibodies as a Correlate of Instantaneous Risk of Hospitalized Dengue in Placebo Recipients of Dengue Vaccine Efficacy Trials.The Journal of infectious diseases · 2022Trial
- Adapting Rapid Diagnostic Tests to Detect Historical Dengue Virus Infections.Frontiers in immunology · 2021Trial
- Fine-scale heterogeneity inProceedings of the National Academy of Sciences of the United States of America · 2020Trial
- Direct Infection of B Cells by Dengue Virus Modulates B Cell Responses in a Cambodian Pediatric Cohort.Frontiers in immunology · 2020Trial
- Bridging Efficacy of a Tetravalent Dengue Vaccine from Children/Adolescents to Adults in Highly Endemic Countries Based on Neutralizing Antibody Response.The American journal of tropical medicine and hygiene · 2019Trial
- Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection.Frontiers in immunology · 2019Trial
- Association of dengue severity with the serotype of infection: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Functional antibody responses and protection against symptomatic dengue.Communications medicine · 2026Review
- Dengue virus envelope epitope-specific antibodies are associated with protection from severe dengue.EMBO molecular medicine · 2026Article
- Molecular and biophysical requirements for B cell receptor-dependent enhancement of dengue virus infection.Journal of virology · 2026Article
- Longitudinal antibody profiling after dengue reveals distinct dynamics by antibody specificity over 18 months.Nature communications · 2026Article
- Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Estimating Enteric Fever Seroincidence in Bangladesh Using Rapid Serosurveys.Open forum infectious diseases · 2026Article
- Investigating antibody cross-reactivity and transmission dynamics of alphaviruses and flaviviruses using a multiplex serological assay.Nature communications · 2026Article
- Enhancing, controlling, and sterilizing dengue immunity and the development of broadly protective responses.medRxiv : the preprint server for health sciences · 2026Article
- CD8+ T cells and Humoral Immunity Influence the Development of Antibody-Dependent Enhancement: Implications for Vaccine Design.bioRxiv : the preprint server for biology · 2026Article
- Kinetics of antibodies and risk of respiratory syncytial virus infection: a longitudinal cohort in Taizhou City, eastern China.BMC medicine · 2026Article
- Development and optimization of self-collected, field stable, saliva-based immunoassays for scalable epidemiological surveillance of pathogen-specific immunity.medRxiv : the preprint server for health sciences · 2026Article
142 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors.
Henrik SaljeMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Paris, France. henrik.salje@pasteur.fr.
Derek A T CummingsDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Isabel Rodriguez-BarraquerUniversity of California, San Francisco, San Francisco, CA, USA.
Leah C KatzelnickDepartment of Biology, University of Florida, Gainesville, FL, USA.
Justin LesslerDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Chonticha KlungthongDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Butsaya ThaisomboonsukDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Ananda NisalakDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Alden WegDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Damon EllisonDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Louis MacareoDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
In-Kyu YoonInternational Vaccine Institute, Seoul, South Korea.
Richard JarmanViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Stephen ThomasDepartment of Medicine, Upstate Medical University of New York, Syracuse, NY, USA.
Alan L RothmanInstitute for Immunology and Informatics, Department of Cell and Molecular Biology, University of Rhode Island, Providence, RI, USA.
Timothy EndyDepartment of Medicine, Upstate Medical University of New York, Syracuse, NY, USA.
Simon CauchemezMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Paris, France.
Funding
VIRAL DETERMINANTS OF SEVERE DENGUE DISEASEP01AI034533 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ROTHMAN, ALAN L · 1994 to 2022
$42.0MLINKING ANTIGENIC & GENETIC VARIATION OF DENGUE TO INDIVIDUAL AND POPULATION RISKR01AI114703 · NIAID · UNIVERSITY OF FLORIDA · PI CUMMINGS, DEREK A · 2015 to 2019
$3.6MNIAID NIH HHS P01 AI034533NIAID NIH HHS R01 AI114703
Abstract
As with many pathogens, most dengue infections are subclinical and therefore unobserved
Indexed as
Disease SusceptibilityAdolescentAntibodies, ViralBayes TheoremChildCohort StudiesDengueDengue VaccinesHemagglutination Inhibition TestsHumansModels, BiologicalRiskSeasonsAntibodies, ViralDengue Vaccines
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.