ArticleNature2018
Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Abstract read
In one paragraph
Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed.
- Manipulation of nonclassical ubiquitin signaling by pathogenic bacteria.Current opinion in microbiology · 2026Review
- Ubiquitination and autophagy in host-pathogen interactions: from immune surveillance to therapeutic targeting.Nature reviews. Immunology · 2026Review
- Article
- Article
- Post-translational weapons of microbial warfare: how bacterial effectors hijack host cell death and xenophagy.Cell communication and signaling : CCS · 2025Review
- A survey of ADP-ribosyltransferase families in the pathogenic Legionella.BMC genomics · 2025Article
- Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1.Nature communications · 2025Article
- Pathogen-induced rerouting of host membrane trafficking.Current opinion in cell biology · 2025Review
- Article
- Review
- Covalent Probes To CaptureJournal of the American Chemical Society · 2024Article
- Legionella pneumophila evades host-autophagic clearance using phosphoribosyl-polyubiquitin chains.Nature communications · 2024Article
- Phosphoribosyl modification of poly-ubiquitin chains at the Legionella-containing vacuole prohibiting autophagy adaptor recognition.Nature communications · 2024Article
- Sde proteins coordinate ubiquitin utilization and phosphoribosylation to establish and maintain the Legionella replication vacuole.Nature communications · 2024Article
- Review
- Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs.Nature chemical biology · 2024Article
- Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.Nature communications · 2024Article
- The ubiquitin codes in cellular stress responses.Protein & cell · 2024Review
- CapturingFrontiers in molecular biosciences · 2024Article
- Legionella pneumophila-mediated host posttranslational modifications.Journal of molecular cell biology · 2023Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
11 authors.
Anil AkturkWeill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
David J WasilkoWeill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Xiaochun WuWeill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Yao LiuPurdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Yong ZhangPurdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Jiazhang QiuPurdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Zhao-Qing LuoPurdue Institute of Immunology, Inflammation and Infectious Disease and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.
Katherine H ReiterDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Peter S BrzovicDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Rachel E KlevitDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Yuxin MaoWeill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA. ym253@cornell.edu.
Funding
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6MOverall (pp. 40-62)P41GM103485 · NIGMS · CORNELL UNIVERSITY · PI CERIONE, RICHARD A. · 2012 to 2018
$15.5MStructural and Functional Characterization of BRCA1/BARD1R01GM088055 · NIGMS · UNIVERSITY OF WASHINGTON · PI KLEVIT, RACHEL E · 2009 to 2020
$6.5MEffector-mediated Ubiquitin Manipulation in Legionella Pneumophila PathogenesisR01AI127465 · NIAID · PURDUE UNIVERSITY · PI Qing Deng · 2017 to 2026
$3.4MUnconventional Interactions of Human Ubiquitin Conjugating EnzymesR01GM098503 · NIGMS · UNIVERSITY OF WASHINGTON · PI BRZOVIC, PETER S · 2012 to 2016
$1.5MTHE MECHANISM OF A NOVEL FAMILY OF BACTERIAL UBIQUITIN E3 LIGASES IMPORTANT FOR PHAGOSOME REMODELINGR01GM116964 · NIGMS · CORNELL UNIVERSITY · PI MAO, YUXIN · 2016 to 2019
$1.3MEmerging Mechanistic Strategies of RING-Between-RING Ubiquitin LigasesF32GM120797 · NIGMS · UNIVERSITY OF WASHINGTON · PI REITER, KATHERINE · 2017 to 2018
$116kNIAID NIH HHS R01 AI127465NIGMS NIH HHS F32 GM120797NIGMS NIH HHS P41 GM103393NIGMS NIH HHS P41 GM103485NIGMS NIH HHS R01 GM088055NIGMS NIH HHS R01 GM098503NIGMS NIH HHS R01 GM116964NIH HHS 1 F32 GM120797NIH HHS 1R01GM098503-05
Abstract
Ubiquitination is a post-translational modification that regulates many cellular processes in eukaryotes
Indexed as
UbiquitinationAdenosine DiphosphateADP Ribose TransferasesBacterial ProteinsCrystallography, X-RayLegionella pneumophilaLysineMembrane ProteinsModels, MolecularPhosphoric Diester HydrolasesProtein DomainsProtein Processing, Post-TranslationalSerineUbiquitinAdenosine DiphosphateADP Ribose TransferasesBacterial ProteinsLysineMembrane ProteinsPhosphoric Diester HydrolasesSdeA protein, Legionella pneumophilaSerineUbiquitin
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.