ArticleJournal of perinatology : official journal of the California Perinatal Association2018
Second trimester serum cortisol and preterm birth: an analysis by timing and subtype.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Neonatal Hair Cortisol and Birth Outcomes: An Empirical Study and Meta-Analysis.Psychosomatic medicine · 2024Pooled it
- Is there a maternal blood biomarker that can predict spontaneous preterm birth prior to labour onset? A systematic review.PloS one · 2022Pooled it
- Neuroactive steroids in the programming of neurodevelopment: implications of maternal obesity.Frontiers in endocrinology · 2025Review
- Association of pica with cortisol and inflammation among Latina pregnant women.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- Perinatal Stressors and Consequences for Neonates with Critical Congenital Heart Disease.Journal of cardiovascular development and disease · 2023Article
- A framework for testing pathways from prenatal stress-responsive hormones to cardiovascular disease risk.Frontiers in endocrinology · 2023Review
- Enduring impact of childhood adversity: Affective modulation of acoustic startle response during pregnancy and postpartum.Physiology & behavior · 2023Article
- Associations between maternal awakening salivary cortisol levels in mid-pregnancy and adverse birth outcomes.Archives of gynecology and obstetrics · 2022Article
- Effect of individual or comorbid antenatal depression and anxiety on birth outcomes and moderation by maternal traumatic experiences and resilience.Journal of affective disorders reports · 2022Article
- A Nested Case-Control Study of the Relationship between Salivary Inflammatory Mediators, Periodontal Parameters, and Preterm Birth in a Chinese Population.BioMed research international · 2022Article
- Antepartum Depression and Preterm Birth: Pathophysiology, Epidemiology, and Disparities due to structural racism.Current psychiatry reports · 2021Review
- Stress and Metabolomics for Prediction of Spontaneous Preterm Birth: A Prospective Nested Case-Control Study in a Tertiary Hospital.Frontiers in pediatrics · 2021Article
- The Risk of Preterm Birth in Women with Three Consecutive Deliveries-The Effect of Number and Type of Prior Preterm Births.Journal of clinical medicine · 2020Article
- Paternal violent criminality and preterm birth: a Swedish national cohort study.BMC pregnancy and childbirth · 2020Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveWe hypothesized second trimester serum cortisol would be higher in spontaneous preterm births compared to provider-initiated (previously termed 'medically indicated') preterm births. STUDY
designWe used a nested case-control design with a sample of 993 women with live births. Cortisol was measured from serum samples collected as part of routine prenatal screening. We tested whether mean-adjusted cortisol fold-change differed by gestational age at delivery or preterm birth subtype using multivariable linear regression.
resultAn inverse association between cortisol and gestational age category (trend p = 0.09) was observed. Among deliveries prior to 37 weeks, the mean-adjusted cortisol fold-change values were highest for preterm premature rupture of the membranes (1.10), followed by premature labor (1.03) and provider-initiated preterm birth (1.01), although they did not differ statistically.
conclusionCortisol continues to be of interest as a marker of future preterm birth. Augmentation with additional biomarkers should be explored.
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