Evidence map›Paper›PMID 29795274›Full record

ArticleScientific reports2018

Effect of physical activity on pulse wave velocity in elderly subjects with normal glucose, prediabetes or Type 2 Diabetes.

Erja Metsämarttila, Enrique Rodilla, Jari Jokelainen, Sauli Herrala, Juhani Leppäluoto, Sirkka Keinänen-Kiukaanniemi, Karl-Heinz Herzig

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  6. Observational
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  10. Development of a novel CT-derived measure of cardiovascular health: the CT aortic stiffness index (CTASI).Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Article
  11. Article
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  13. Prevalence of Dyslipidaemia among Type 2 Diabetes Mellitus Patients in the Western Cape, South Africa.International journal of environmental research and public health · 2020
    Article
  14. Physical activity in women with subclinical hypothyroidism.Journal of endocrinological investigation · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Erja MetsämarttilaResearch Unit of Biomedicine, and Biocenter of Oulu, Oulu University, 90014, Oulu, Finland.
Enrique RodillaHypertension Clinic, Internal Medicine, Hospital de Sagunto, Valencia, Spain.
Jari JokelainenCenter for Life Course Epidemiology and Systems Medicine, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland.
Sauli HerralaCenter for Life Course Epidemiology and Systems Medicine, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland.
Juhani LeppäluotoResearch Unit of Biomedicine, and Biocenter of Oulu, Oulu University, 90014, Oulu, Finland.
Sirkka Keinänen-KiukaanniemiCenter for Life Course Epidemiology and Systems Medicine, Faculty of Medicine, University of Oulu, 90014, Oulu, Finland.
Karl-Heinz HerzigResearch Unit of Biomedicine, and Biocenter of Oulu, Oulu University, 90014, Oulu, Finland. Karl-Heinz.Herzig@oulu.fi.
University of Oulu · FIHospital de Sagunto · ESOulu University Hospital · FIPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotid-femoral pulse wave velocity ((cf)PWV) is a measure of arterial stiffness, predicting cardiovascular disease. We hypothesized that the amount of physical activity (PA) is correlated with reduced arterial stiffness in Type 2 diabetic (T2D) subjects. 570 subjects from the 1945 Oulu birth cohort were included in the analysis. (cf)PWV was determined by a non-invasive applanation tonometry. Oral glucose tolerance test was performed and LDL and HDL cholesterol analyzed. PA was registered daily with a wrist-worn acceleration meter for two weeks. (cf)PWV values in subjects with impaired glucose metabolism (IGM) and T2D were higher than in normal glycemic subjects (P < 0.001). PA, fasting and 2 h glucose and HbA1c correlated significantly with (cf)PWV, but HDL or LDL cholesterol did not. The 2 h glucose, heart rate and alcohol consumption in T2D subjects had independent effects on (cf)PWV in multiple regression analysis. T2D and IGM were significantly associated to (cf)PWV. Interestingly, lipids did not have an additional effect on (cf)PWV. Subjects walking more than 10 000 steps/day had 0.2 m/s lower (cf)PWV than those walking less than 6000 steps/day. Presence of T2D, elevated heart rate and alcohol consumption in males were associated with increased aortic stiffening in elderly subjects.

Indexed as

Exercise TherapyPulse Wave AnalysisVascular StiffnessAgedBlood Flow VelocityBlood GlucoseCardiovascular DiseasesCase-Control StudiesCohort StudiesDiabetes Mellitus, Type 2FemaleHumansMalePrediabetic StateRisk FactorsBlood Glucose

Identifiers

PMID29795274
PMCPMC5966452
OpenAlexW2805853835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.