Trial reportPediatric research2018
Predictors of mortality among hospitalized children with severe acute malnutrition: a prospective study from Uganda.
Trial report in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Prevalence and risk factors of under-five mortality due to severe acute malnutrition in Africa: a systematic review and meta-analysis.Systematic reviews · 2025Pooled it
- Pooled it
- Effect of Fish-Based Diet on Malnourished Children: A Systematic Review.Iranian journal of medical sciences · 2024Pooled it
- Predictors of inpatient mortality among children hospitalized for severe acute malnutrition: a systematic review and meta-analysis.The American journal of clinical nutrition · 2020Pooled it
- Trial
- AKI and Mortality in Children Hospitalized With Malnutrition.Kidney international reports · 2026Article
- Exploring nutritional screening tools for hospitalized children: a narrative review.Clinical and experimental pediatrics · 2025Article
- Time to stabilization among under-five children with severe acute malnutrition in Ethiopia: a retrospective cohort study.BMC public health · 2025Article
- Diagnostic criteria for severe acute malnutrition and fatal outcomes in children aged 6-59 months, Nigeria.Bulletin of the World Health Organization · 2025Observational
- Article
- The Spectrum of Pathogens Associated with Infections in African Children with Severe Acute Malnutrition: A Scoping Review.Tropical medicine and infectious disease · 2024Article
- Identification of risk factors for inpatient mortality in infants and children with severe wasting and/or nutritional oedema-what next?European journal of clinical nutrition · 2024Article
- Novel gastrointestinal tools (GI Tools) for evaluating gut functional capacity in adults with environmental enteropathy in Zambia and Zimbabwe: A cross-sectional study protocol.F1000Research · 2024Article
- Risk factors for inpatient mortality among children with severe acute malnutrition in Zimbabwe and Zambia.European journal of clinical nutrition · 2023Observational
- Article
- Determinants of mortality among under-five children admitted with severe acute malnutrition in Addis Ababa, Ethiopia.Nutrition journal · 2021Article
- Weight-for-HeightCurrent developments in nutrition · 2021Article
- Weight and mid-upper arm circumference gain velocities during treatment of young children with severe acute malnutrition, a prospective study in Uganda.BMC nutrition · 2021Article
- Starvation and Its Effects on the Gut.Advances in nutrition (Bethesda, Md.) · 2021Article
- Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe determined the predictors of mortality among children admitted with severe acute malnutrition (SAM).
methodsThis was a prospective study nested in a randomized trial among 6-59-month-old children admitted with SAM. Socio-demographic and medical history data were collected using questionnaires and clinical examination, anthropometry and laboratory tests were performed. They were monitored daily until discharge or death during hospitalization while receiving care according to national guidelines. Predictors of death were assessed using Cox regression.
resultsOf 400 children, 9.8% (n = 39) died during hospitalization. Predictors of mortality included diarrhoea at admission [hazard ratio [HR] 2.19, 95% confidence interval (CI): 1.06; 4.51], lack of appetite [HR 4.50, 95% CI: 1.76; 11.50], suspected sepsis [HR 2.23, 95% CI: 1.18; 4.24] and skin ulcers [HR 4.23, 95% CI: 1.26; 4.17]. Chest indrawing [HR 5.0, 95% CI: 1.53; 16.3], oxygen saturation below 94% [HR 3.92, 95% CI: 1.42; 10.83] and confirmed HIV infection [HR 3.62, 95% CI: 1.69; 7.77] also predicted higher mortality.
conclusionInfections were major contributors to mortality. This underscores the need for improved prevention and management of these infections among children with severe malnutrition.
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