Evidence map›Paper›PMID 29795181›Full record

ArticleScientific reports2018

Low doses of bioherbicide favour prion aggregation and propagation in vivo.

Pierre-André Lafon, Thibaut Imberdis, Yunyun Wang, Joan Torrent, Mike Robitzer, Elisabeth Huetter, Maria-Teresa Alvarez-Martinez, Nathalie Chevallier, Laurent Givalois, Catherine Desrumaux and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Parkinson's Disease: A Prionopathy?International journal of molecular sciences · 2021
    Review
  6. Article
  7. Fungicide Residues Exposure andEnvironmental health perspectives · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Pierre-André LafonMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Thibaut ImberdisMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.ORCID 0000-0002-0818-2617
Yunyun WangMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Joan TorrentMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Mike RobitzerInstitut Charles Gerhardt Montpellier, UMR 5253 CNRS-ENSCM-UM, Matériaux Avancés pour la Catalyse et la Santé, Montpellier, France.
Elisabeth HuetterMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Maria-Teresa Alvarez-MartinezEtablissement Confiné d'Expérimentation A3/L3, CECEMA, US009 Biocampus, UMS 3426, Université Montpellier, Montpellier, F-34095, France.
Nathalie ChevallierMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Laurent GivaloisMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Catherine DesrumauxMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France.
Jianfeng LiuCellular Signaling Laboratory, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Véronique PerrierMMDN, University Montpellier, EPHE, INSERM, U1198- EiAlz team, PSL Research University, Montpellier, F-34095, France. veronique.perrier@umontpellier.fr.ORCID 0000-0002-6570-7504
Inserm · FRBrigham and Women's Hospital · USÉcole Nationale Supérieure de Chimie de Montpellier · FRHuazhong University of Science and Technology · CNUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Public concerns over the use of synthetic pesticides are growing since many studies have shown their impact on human health. A new environmental movement in occidental countries promoting an organic agriculture favours the rebirth of botanical pesticides. These products confer an effective alternative to chemical pesticides such as glyphosate. Among the biopesticides, the α-terthienyls found in the roots of Tagetes species, are powerful broad-spectrum pesticides. We found that an α-terthienyl analogue with herbicidal properties, called A6, triggers resistant SDS oligomers of the pathogenic prion protein PrP

Indexed as

AnimalsBrainDose-Response Relationship, DrugFemaleHumansMiceMice, Inbred C57BLNeuroblastomaPesticidesPrion DiseasesPrPC ProteinsPyrimidinesTumor Cells, CulturedPesticidesPrPC ProteinsPyrimidines

Identifiers

PMID29795181
PMCPMC5966510
OpenAlexW2806187894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.