ReviewLab animal2018
The Drosophila model for microbiome research.
Review in Lab animal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06869941 (Adipose Tissue Gene Expression and Metabolomics Links to the Gut Microbiome-brain Axis), which is not on this map. Cited by 98 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adipose Tissue Gene Expression and Metabolomics Links to the Gut Microbiome-brain Axis (POINSETTIA Study)
Who cites it
98 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Functional Equivalence and Conserved Sexual Dimorphism in the Gut Microbiome: A Cross-Species Meta-analysis.Journal of molecular evolution · 2026Pooled it
- Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila melanogaster.BMC microbiology · 2021Pooled it
- Review
- A Landscape ofBiology · 2026Review
- Molecular Mechanisms of Gut Microbiota-Immune System Crosstalk: From Mucosal Architecture to Adaptive Immunity Programming.International journal of molecular sciences · 2026Review
- A dataset on habitat-associated changes in the fecal microbiota of Drosophila melanogaster.Scientific data · 2026Article
- Host genetics and diet jointly shape the microbiome of Drosophila melanogaster but do not predict lifespan or age-related traits.Biogerontology · 2026Article
- Life-Stage-Dependent Variation in Gastrointestinal Microbial Communities of Drosophila melanogaster.Microbial ecology · 2026Article
- Phylosymbiosis and functional redundancy in the Drosophila (Diptera: Drosophilidae) gut microbiome and its implications for host fitness.Journal of insect science (Online) · 2026Article
- Dietary allyl-isothiocyanate affects male triglyceride levels inFrontiers in microbiology · 2026Article
- Whole-body homogenates restore disrupted microbiota composition in a model insect better than feces or no restoration treatment.bioRxiv : the preprint server for biology · 2025Article
- Microbiome composition and co-occurrence dynamics in wildMicrobiology spectrum · 2025Article
- Phylogenetic and functional diversity amongmSystems · 2025Article
- Host specificity of gut microbiota associated with social bees: patterns and processes.Microbiology and molecular biology reviews : MMBR · 2025Review
- Gut microbiome and host TOR pathway interact to regulate predator-induced aversive memory inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Chromosomal Inversions in Chromosome U ofInsects · 2025Article
- Review
- Microbial solutions to dietary stress: experimental evolution reveals host-microbiome interplay inProceedings. Biological sciences · 2025Article
- Different Long-Term Nutritional Regimens ofInsects · 2025Article
- Transmission of yeast and bacterial symbionts between sexual partners inRoyal Society open science · 2025Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The gut microbiome is increasingly recognized to play an important role in shaping the health and fitness of animals, including humans. Drosophila is emerging as a valuable model for microbiome research, combining genetic and genomic resources with simple protocols to manipulate the microbiome, such that microbiologically sterile flies and flies bearing a standardized microbiota can readily be produced in large numbers. Studying Drosophila has the potential to increase our understanding of how the microbiome influences host traits, and allows opportunities for hypothesis testing of microbial impacts on human health. Drosophila is being used to investigate aspects of host-microbe interactions, including the metabolism, the immune system and behavior. Drosophila offers a valuable alternative to rodent and other mammalian models of microbiome research for fundamental discovery of microbiome function, enabling improved research cost effectiveness and benefits for animal welfare.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.