Evidence map›Paper›PMID 29795118›Full record

ArticleScientific reports2018

Profiling dendritic cell subsets in head and neck squamous cell tonsillar cancer and benign tonsils.

Milad Abolhalaj, David Askmyr, Christina Alexandra Sakellariou, Kristina Lundberg, Lennart Greiff, Malin Lindstedt

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
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  4. Application of single-cell RNA sequencing in head and neck squamous cell carcinoma.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Milad AbolhalajDepartment of Immunotechnology, Lund University, Lund, Sweden.
David AskmyrDepartment of ORL, Head & Neck Surgery, Skåne University Hospital, Lund, Sweden.
Christina Alexandra SakellariouDepartment of Immunotechnology, Lund University, Lund, Sweden.
Kristina LundbergDepartment of Immunotechnology, Lund University, Lund, Sweden.
Lennart GreiffDepartment of ORL, Head & Neck Surgery, Skåne University Hospital, Lund, Sweden.
Malin LindstedtDepartment of Immunotechnology, Lund University, Lund, Sweden. malin.lindstedt@immun.lth.se.
Lund University · SESkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) have a key role in orchestrating immune responses and are considered important targets for immunotherapy against cancer. In order to develop effective cancer vaccines, detailed knowledge of the micromilieu in cancer lesions is warranted. In this study, flow cytometry and human transcriptome arrays were used to characterize subsets of DCs in head and neck squamous cell tonsillar cancer and compare them to their counterparts in benign tonsils to evaluate subset-selective biomarkers associated with tonsillar cancer. We describe, for the first time, four subsets of DCs in tonsillar cancer: CD123

Indexed as

Gene Expression ProfilingBiomarkers, TumorCarcinoma, Squamous CellCells, CulturedDendritic CellsHumansPalatine TonsilTonsillar NeoplasmsBiomarkers, Tumor

Identifiers

PMID29795118
PMCPMC5966442
OpenAlexW2807473407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.