ArticleMedical science monitor : international medical journal of experimental and clinical research2018
Marital Status and Survival of Patients with Hormone Receptor-Positive Male Breast Cancer: A Surveillance, Epidemiology, and End Results (SEER) Population-Based Study.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Marital status and competing risks of mortality in non-small cell lung cancer: a SEER-based nomogram analysis.Journal of thoracic disease · 2025Article
- Predicting Overall Survival in Patients with Male Breast Cancer: Nomogram Development and External Validation Study.JMIR cancer · 2025Article
- Epidemiological and survival outcomes of neuroendocrine carcinoma of the breast: a SEER data analysis.Translational cancer research · 2023Article
- Quality of Life in Breast Cancer Survivors in Relation to Age, Type of Surgery and Length of Time since First Treatment.International journal of environmental research and public health · 2022Article
- Article
- Male breast cancer: an update.Virchows Archiv : an international journal of pathology · 2022Review
- Influence of marital status on the treatment and survival of middle-aged and elderly patients with primary bone cancer.Frontiers in medicine · 2022Article
- The effect of marital and insurance status on the survival of elderly patients with stage M1b colon cancer: a SEER-based study.BMC cancer · 2021Article
- Effects of marital status on overall and cancer-specific survival in laryngeal cancer patients: a population-based study.Scientific reports · 2021Article
- Marital Status and Survival in Osteosarcoma Patients: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Incidence and survival outcomes of early male breast cancer: a population-based comparison with early female breast cancer.Annals of translational medicine · 2019Article
- Impact of Insurance Status on Stage, Treatment, and Survival in Patients with Colorectal Cancer: A Population-Based Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
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Abstract
BACKGROUND Although marital status has been reported as a prognostic factor in different cancer types, its prognostic effect on hormone receptor (HR) positive male breast cancer (MBC) is unclear. The objective of the present analysis was to assess the effects of marital status on survival in patients with HR positive MBC. MATERIAL AND METHODS Patients diagnosed with HR positive MBC from 1990 to 2014 in the Surveillance, Epidemiology, and End Results (SEER) database were included. Kaplan-Meier survival analysis and Cox proportional hazard regression were used to identify the effects of marital status on cancer-specific survival (CSS) and overall survival (OS). RESULTS A total of 3612 cases were identified in this study. Married patients had better 5-year CSS and 5-year OS than unmarried men. In multivariate Cox regression models, unmarried patients also showed higher mortality risk for both CSS and OS, independent of age, race, grade, stage, PR status, HER2 status, and surgery. Subgroup survival analysis according to different ER/PR status showed that married patients had beneficial CSS results only in ER+/PR+ subtype, and CSS in the married and unmarried groups did not significantly differ by TNM stage. The results were further confirmed in the 1: 1 matched group. CONCLUSIONS Marital status was an important prognostic factor for survival in patients with HR positive MBC. Unmarried patients are at greater risk of death compared with married groups. The survival benefit for married patients remained even after adjustment, which indicates the importance of spousal support in MBC.
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