ArticleGenes2018
Transitions from Single- to Multi-Locus Processes during Speciation with Gene Flow.
Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Evolution of genome-wide barriers to gene flow during complex speciation in rattlesnakes.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Estimation of genome-wide coupling in rattlesnake hybrids provides insight into the process of speciation and its progress.Nature communications · 2025Article
- Coupling of Barriers to Gene Exchange: Causes and Consequences.Cold Spring Harbor perspectives in biology · 2024Review
- Quantitative Analyses of Coupling in Hybrid Zones.Cold Spring Harbor perspectives in biology · 2023Review
- Article
- The Genomic Landscape of Divergence Across the Speciation Continuum in Island-Colonising Silvereyes (G3 (Bethesda, Md.) · 2020Article
- Multi-locus interactions and the build-up of reproductive isolation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Host plant-related genomic differentiation in the European cherry fruit fly, Rhagoletis cerasi.Molecular ecology · 2019Article
- Genome-wide association analyses reveal polygenic genomic architecture underlying divergent shell morphology in SpanishEcology and evolution · 2019Article
- The population genomics of multiple tsetse fly (Glossina fuscipes fuscipes) admixture zones in Uganda.Molecular ecology · 2019Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
During speciation-with-gene-flow, a transition from single-locus to multi-locus processes can occur, as strong coupling of multiple loci creates a barrier to gene flow. Testing predictions about such transitions with empirical data requires building upon past theoretical work and the continued development of quantitative approaches. We simulated genomes under several evolutionary scenarios of gene flow and divergent selection, extending previous work with the additions of neutral sites and coupling statistics. We used these simulations to investigate, in a preliminary way, if and how selected and neutral sites differ in the conditions they require for transitions during speciation. For the parameter combinations we explored, as the per-locus strength of selection grew and/or migration decreased, it became easier for selected sites to show divergence-and thus to rise in linkage disequilibrium (LD) with each other as a statistical consequence-farther in advance of the conditions under which neutral sites could diverge. Indeed, even very low rates of effective gene flow were sufficient to prevent differentiation at neutral sites. However, once strong enough, coupling among selected sites eventually reduced gene flow at neutral sites as well. To explore whether similar transitions might be detectable in empirical data, we used published genome resequencing data from three taxa of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.