Evidence map›Paper›PMID 29794832›Full record

ArticleAIDS (London, England)2018

Preference for injectable over oral HIV pre-exposure prophylaxis in public-sector primary-care clinics in Swaziland.

Mark J Siedner, Anita Hettema, Allison Hughey, Catherine E Oldenburg, Stefan Kohler, Kate Bärnighausen, Shannon McMahon, Chuan Jia, Charlotte Lejeune, Sindy Matse and 1 more

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Mark J SiednerMassachusetts General Hospital.
Anita HettemaClinton Health Access Initiative, Mbabane, Swaziland.
Allison HugheyClinton Health Access Initiative, Mbabane, Swaziland.
Catherine E OldenburgUniversity of California San Francisco, San Francisco, California, USA.
Stefan KohlerUniversity of Heidelberg, Heidelberg, Germany.
Kate BärnighausenUniversity of Heidelberg, Heidelberg, Germany.
Shannon McMahonUniversity of Heidelberg, Heidelberg, Germany.
Chuan JiaUniversity of Heidelberg, Heidelberg, Germany.
Charlotte LejeuneClinton Health Access Initiative, Mbabane, Swaziland.
Sindy MatseSwaziland Ministry of Health, Mbababane, Swaziland.
Till BärnighausenAfrica Health Research Institute, KwaZulu-Natal, South Africa.
Heidelberg University · DEClinton Health Access Initiative · USAfrica Health Research Institute · ZAMbarara University of Science and Technology · UGUniversity of California, San Francisco · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
SOCIAL AND ECONOMIC PREDICTORS OF PHYSICAL AND COGNITIVE FUNCTIONP01AG041710 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI LISA F BERKMAN, THOMAS A GAZIANO · 2013 to 2026
$37.3M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Training Tanzanian Researchers for HIV/AIDS Implementation ScienceD43TW009775 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, Christopher Sudfeld · 2015 to 2026
$3.0M
New Methods for the design and evaluation of large HIV prevention interventionsR01AI112339 · NIAID · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2017
$2.7M
Causal Pathways to population health impact of HIV antiretroviral treatmentR01HD084233 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2015 to 2021
$2.3M
Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South AfricaR01AI124389 · NIAID · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2016 to 2020
$2.1M
Behavioral Aspects of Low-cost Medical Devices to Improve HIV CareK23MH099916 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2013 to 2017
$917k
FIC NIH HHS D43 TW009775NIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI112339NIAID NIH HHS R01 AI124389NIA NIH HHS P01 AG041710NICHD NIH HHS R01 HD084233NIMH NIH HHS K23 MH099916NIMH NIH HHS R25 MH083620Wellcome Trust
6 · The paper itself

Abstract

: Long-acting injectable (LAI) HIV pre-exposure prophylaxis (PrEP) may mitigate adherence challenges reported by young women in Southern Africa. We assessed preferences for PrEP in public-sector, primary care clinics in Swaziland. Among surveyed respondents, 75% (95% confidence interval = 65-83%) stated preference for LAI over oral PrEP; with no differences by sex, age, or sexual behavior (all P > 0.05). Notably, over 70% (95% confidence interval 58-82%) with current use of oral PrEP also stated preference for LAI PrEP.

Indexed as

Public SectorAdolescentAdultAnti-HIV AgentsDelayed-Action PreparationsEswatiniFemaleHIV InfectionsHumansInjectionsMaleMiddle AgedPre-Exposure ProphylaxisPrimary Health CareYoung AdultAnti-HIV AgentsDelayed-Action Preparations

Identifiers

PMID29794832
PMCPMC6717317
OpenAlexW2804603775

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.