Evidence map›Paper›PMID 29794798›Full record

ArticleMedicine2018

Colonic metastasis from breast carcinoma detection by CESM and PET/CT: A case report.

Giuseppe Falco, Simone Mele, Maurizio Zizzo, Graziella Di Grezia, Paolo Cecinato, Giulia Besutti, Saverio Coiro, Gianluca Gatta, Rita Vacondio, Guglielmo Ferrari

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Rare sites of breast cancer metastasis: a review.Translational cancer research · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giuseppe FalcoDepartment of Oncology and Advanced Technologies, Breast Surgery Unit, IRCSS Santa Maria Nuova Hospital, Reggio Emilia Department of Oncology and Advanced Technologies, Surgical Oncology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena Radiology Department, Criscuoli Hospital, Sant' Angelo dei Lombardi, Avellino Department of Oncology and Advanced Technologies, Gastroenterology-Digestive Endoscopy Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia Department of Imaging and Medicine of Laboratory, Radiology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia Radiology Department, "Luigi Vanvitelli" University of Campania, Naples, Italy.
Simone Mele
Maurizio Zizzo
Graziella Di Grezia
Paolo Cecinato
Giulia Besutti
Saverio Coiro
Gianluca Gatta
Rita Vacondio
Guglielmo Ferrari
Santa Maria Nuova Hospital · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMetastatic spread in invasive lobular carcinoma (ILC) of breast mainly occurs in bones, gynecological organs, peritoneum, retroperitoneum, and gastrointestinal (GI) tract. Metastases to the GI tract may arise many years after initial diagnosis and can affect the tract from the tongue to the anus, stomach being the most commonly involved site. Clinical presentations are predominantly nonspecific, and rarely asymptomatic. CEA, CA 15-3, and CA 19-9 may be informative for symptomatic patients who have had a previous history of breast cancer. CASE PRESENTATION: We introduce the case of asymptomatic colonic metastasis from breast carcinoma in a 67-year-old woman followed-up for Luminal A ILC. Diagnosis was performed through positron emission tomography/computed tomography (PET/CT) scan and contrast-enhancement spectral mammography (CESM), steering endoscopist to spot the involved intestinal tract and in ruling out further dissemination in the breast parenchyma.

conclusionIn colonic metastases, tumor markers might not be totally reliable. In asymptomatic cases, clinical conditions might be underappreciated, missing local or distant recurrence. CT and PET/CT scan might be useful in diagnosing small volume diseases, and steering endoscopist toward GI metastasis originating from the breast. CESM represents a tolerable and feasible tool that rules out multicentricity and multifocality of breast localization. Moreover, particular patients could tolerate it better than magnetic resonance imaging (MRI).

Indexed as

AgedAsymptomatic DiseasesBreastBreast NeoplasmsCarcinoma, LobularColectomyColonColonic NeoplasmsColonoscopyFemaleFluorodeoxyglucose F18HumansMammographyMucin-1Neoplasm InvasivenessNeoplasm Metastasiscarcinoembryonic antigen binding protein, humanFluorodeoxyglucose F18Mucin-1Receptors, Cell Surface

Identifiers

PMID29794798
PMCPMC6392653
OpenAlexW2804498718

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.