Evidence map›Paper›PMID 29794225›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Depicting Changes in Tumor Biology in Response to Cetuximab Monotherapy or Combination Therapy by Apoptosis and Proliferation Imaging Using

Kathrin Heinzmann, Quang-Dé Nguyen, Davina Honess, Donna-Michelle Smith, Stephen Stribbling, Diana Brickute, Chris Barnes, John Griffiths, Eric Aboagye

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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  4. Development of [Cancers · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kathrin HeinzmannDepartment of Surgery and Cancer, Imperial College London, London, United Kingdom; and.
Quang-Dé NguyenDepartment of Surgery and Cancer, Imperial College London, London, United Kingdom; and.
Davina HonessCancer Research U.K. Cambridge Institute, Cambridge, United Kingdom.
Donna-Michelle SmithCancer Research U.K. Cambridge Institute, Cambridge, United Kingdom.
Stephen StribblingDepartment of Surgery and Cancer, Imperial College London, London, United Kingdom; and.
Diana BrickuteDepartment of Surgery and Cancer, Imperial College London, London, United Kingdom; and.
Chris BarnesDepartment of Surgery and Cancer, Imperial College London, London, United Kingdom; and.
John GriffithsCancer Research U.K. Cambridge Institute, Cambridge, United Kingdom.
Eric AboagyeDepartment of Surgery and Cancer, Imperial College London, London, United Kingdom; and eric.aboagye@imperial.ac.uk.
Imperial College London · GBCancer Research UK Cambridge Center · GB

Funding

Cancer Research UK 11562
6 · The paper itself

Abstract

Imaging biomarkers must demonstrate their value in monitoring treatment. Two PET tracers, the caspase-3/7-specific isatin-5-sulfonamide

Indexed as

AzidesDideoxynucleosidesIndolesPositron-Emission TomographyAnimalsApoptosisCell ProliferationCell Transformation, NeoplasticCetuximabDeoxycytidineDrug InteractionsGemcitabineHCT116 CellsHumansLung NeoplasmsMice(18)F-ICMT11alovudineAzidesCetuximabDeoxycytidineDideoxynucleosidesGemcitabineIndolesKRAS protein, humanNucleosidesProto-Oncogene Proteins p21(ras)anti-EGFR-based therapyapoptosisPET imagingproliferation

Identifiers

PMID29794225
PMCPMC6167530
OpenAlexW2804972485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.