Evidence map›Paper›PMID 29794142›Full record

ArticleHaematologica2018

Frequency, risk factors, and impact on mortality of arterial thromboembolism in patients with cancer.

Ella Grilz, Oliver Königsbrügge, Florian Posch, Manuela Schmidinger, Robert Pirker, Irene M Lang, Ingrid Pabinger, Cihan Ay

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Haemostasis and the Need for Antithrombotics: An Introduction.Handbook of experimental pharmacology · 2026
    Review
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  7. Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ella GrilzClinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria.
Oliver KönigsbrüggeClinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria.
Florian PoschClinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria.
Manuela SchmidingerClinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Austria.
Robert PirkerClinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Austria.
Irene M LangClinical Division of Cardiology, Department of Medicine II, Medical University of Vienna, Austria.
Ingrid PabingerClinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria.
Cihan AyClinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Austria cihan.ay@meduniwien.ac.at.
Medical University of Vienna · AT

Funding

Austrian Science Fund FWF F 5405
6 · The paper itself

Abstract

In contrast to venous thromboembolism, little is known about arterial thromboembolism in patients with cancer. The aim of this study was to quantify the risk and explore clinical risk factors of arterial thromboembolism in patients with cancer, and investigate its potential impact on mortality. Patients with newly-diagnosed cancer or progression of disease after remission were included in a prospective observational cohort study and followed for two years. Between October 2003 and October 2013, 1880 patients (54.3% male; median age 61 years) were included. During a median follow up of 723 days, 48 (2.6%) patients developed arterial thromboembolism [20 (41.7%) myocardial infarction, 16 (33.3%) stroke and 12 (25.0%) peripheral arterial events], 157 (8.4%) developed venous thromboembolism, and 754 (40.1%) patients died. The cumulative 3-, 6-, 12-, and 24-month risks of arterial thromboembolism were 0.9%, 1.1%, 1.7%, and 2.6%, respectively. Male sex (subdistribution hazard ratio=2.9, 95%CI: 1.5-5.6;

Indexed as

AgedAustriaComorbidityDisease ProgressionFemaleHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedNeoplasmsPatient Outcome AssessmentPrognosisRegistriesRisk AssessmentRisk Factors

Identifiers

PMID29794142
PMCPMC6119137
OpenAlexW2804174942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.