Evidence map›Paper›PMID 29794140›Full record

ArticleThe Journal of biological chemistry2018

The stimulatory G protein G

Brandon Podyma, Hui Sun, Eric A Wilson, Bradley Carlson, Ethan Pritikin, Oksana Gavrilova, Lee S Weinstein, Min Chen

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Parental Origin ofJBMR plus · 2022
    Article
  13. Article
  14. Review
  15. The central melanocortin system and human obesity.Journal of molecular cell biology · 2020
    Review
  16. Article
  17. Article
  18. Frontiers in endocrinology · 2020
    Article
  19. Management of pseudohypoparathyroidism.Current opinion in pediatrics · 2019
    Review
  20. GMolecular metabolism · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Brandon PodymaFrom the Metabolic Diseases Branch and.
Hui SunFrom the Metabolic Diseases Branch and.
Eric A WilsonFrom the Metabolic Diseases Branch and.
Bradley CarlsonFrom the Metabolic Diseases Branch and.
Ethan PritikinFrom the Metabolic Diseases Branch and.
Oksana GavrilovaMouse Metabolism Core Laboratory, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
Lee S WeinsteinFrom the Metabolic Diseases Branch and leew@mail.nih.gov.
Min ChenFrom the Metabolic Diseases Branch and minc@niddk.nih.gov.
National Institutes of Health · US

Funding

Metabolic Studies of Mouse Models of Obesity and DiabetesZICDK070002 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI GAVRILOVA, OKSANA · 2009 to 2025
$15.0M
Role of Gs-alpha in central regulation of energy and glucose metabolismZIADK043315 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WEINSTEIN, LEE · 2009 to 2025
$9.0M
Studies Of Pseudohypoparathyroidism And Related DisordersZIADK043302 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WEINSTEIN, LEE · 2009 to 2025
$5.8M
Role of the Gnas Gene in Metabolic RegulationZIADK043313 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WEINSTEIN, LEE · 2009 to 2025
$4.9M
6 · The paper itself

Abstract

Central melanocortin 4 receptors (MC4Rs) stimulate energy expenditure and inhibit food intake. MC4Rs activate the G protein G

Indexed as

Energy MetabolismThermogenesisAnimalsEatingFemaleGenomic ImprintingGlucoseGTP-Binding Protein alpha Subunits, GsHomozygoteMaleMiceMice, Inbred C57BLMice, KnockoutObesityReceptor, Melanocortin, Type 4GlucoseGTP-Binding Protein alpha Subunits, GsMC4R protein, mouseReceptor, Melanocortin, Type 4cyclic AMP (cAMP)energy metabolismglucose metabolismG protein-coupled receptorheterotrimeric G proteinmetabolic regulationmouse geneticsneurosciencesignal transduction

Identifiers

PMID29794140
PMCPMC6052205
OpenAlexW2803697991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.